collecting duct


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collecting duct

that part of the renal tubule in a kidney in which water absorption takes place under the control of ADH, producing a urine of variable concentration depending on overall water levels in the body.
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9) In 1997, the Heidelberg classification of renal tumours identified 5 histologic types of renal cancer: conventional, papillary, chromophobe, collecting duct, and unclassifiable.
Originally, TCC was believed to be a subtype of collecting duct carcinoma that was first described by Masson, who coined the moniker "Bellinian epithelioma" or "carcinoma of the collecting ducts" because he thought it originated from collecting ducts of Bellini (1).
Previously referred to as 'low-grade collecting duct carcinoma' or 'Bellinian epithelioma', tubulocystic renal cell carcinoma (TC-RCC) is a unique, recently identified subtype of renal cell carcinoma.
Senior study author Juan Carlos Izpisua Belmonte, a professor in Salk's Gene Expression Laboratory and holder of the Roger Guillemin Chair said that they have developed a simple and efficient method that allows for the differentiation of human stem cells into well-organized 3D structures of the ureteric bud (UB), which later develops into the collecting duct system.
Without vasopressin signaling, the renal collecting duct becomes impermeable to water reabsorption, and the urine quickly becomes very dilute (< 100 mOsm/kg [H.
4,6-9) During nephrogenesis, both PAX8 and PAX2 are expressed very early in the renal blastema and later in collecting duct cells, and all progenitor epithelial cells of the developing nephron.
Character 1: Collecting duct morphology: The collecting ducts of the kidney exit the kidney laterally and communicate with the Wolffian duct individually along the entire length of the Wolffian duct that runs adjacent to the pelvic kidney (state 0).
MDCK (Madin-Canine Kidney collecting duct tubular epithelium cell line) and LLC-PK1 (Porcine Kidney Proximal Tubular epithelial cell line) cells were purchased from ATCC (Rockville, MD, USA).
Since the transit time from collecting duct to bladder is estimated to be around 5 to 7 min, crystal retention is necessary for stone formation of a clinically significant size.
Without the concentrating effect of the medulla, water has less of an osmotic driving force to leave the collecting duct system, ultimately resulting in increased urine production.
There is excretion of potassium in the distal tubule and collecting duct, which is controlled by aldosterone.
Weir said, because the kidney develops homeostatic mechanisms mediated by an increase in sodium potassium adenosinetriphosphatase activity in the renal tubular epithelial cells of the cortical collecting duct.

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