collagenase /col·la·ge·nase/ (kah-laj´ĕ-nās) an enzyme that catalyzes the hydrolysis of peptide bonds in triple helical regions of collagen.
collagenase
collagenase (kol´
jnās´),
col·lag·e·nase (k -l j -n s , -nz, k l-j-)n. Any of various enzymes that catalyze the hydrolysis of collagen and gelatin. |
collagenase
[kəlaj′ənās]
a medication applied as an ointment for debridement of decubitus ulcers, burns, and other epidermal lesions. It is also injected into the penis for treatment of Peyronie's disease and into the wrist, ankle, etc. for the treatment of Dupuytren's disease (restricted movement caused by thickening of the fascia). It is an enzyme preparation derived from the fermentation of Clostridium histolyticum.
collagenase (kol´
jnās´),n an enzyme capable of depolymerizing collagen, found in some microorganisms and believed to contribute to periodontal disease.
collagenase
an enzyme that catalyzes the degradation of collagen.
collagenase ulceration
a rapidly spreading ulceration of the cornea triggered by the liberation of collagenase from necrotic cells.
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