There seems to be a follicle-specificity in enzymatic treatment and digestion protocol and in this study, collagenase IV was superior to collagenase I for retrieving large number of oocytes without losing morphological normality.
In conclusion, enzymatic digestion of porcine ovarian cortex with collagenase is a useful tool for retrieving porcine preantral follicles of different stages.
Collagenase is a drug that breaks down collagen in damaged tissue and helps healthy tissue to grow.
The most potent collagenase is the "crude" collagenase secreted by the anaerobic bacteria "Clostridium histolyticum".
The enzyme collagenase is derived from the fermentation by "Clostridium histolyticum".
Pharmacology: Used in the treatment of skin ulcers and sever burns, collagenase is able to digest collagen in necrotic tissue at physiological pH.
Collagenase is a protease that is specific to collagen.
NCI, a database of ligands where the chemical structure of the drug collagenase is drawn in editor page and the data is transferred to query page.