collagen vascular disease


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Related to collagen vascular disease: Connective tissue disease

collagen vascular disease

n.
Any of a group of inflammatory, often autoimmune diseases affecting connective tissue, including lupus erythematosus, rheumatoid arthritis, and scleroderma. Also called collagen disease.

collagen vascular disease

any of a group of acquired disorders that have in common diffuse immunological and inflammatory changes in small blood vessels and connective tissue. Common features include arthritis, skin lesions, iritis and episcleritis, pericarditis, pleuritis, subcutaneous nodules, myocarditis, vasculitis, and nephritis. Also often associated are Coombs' test-positive hemolytic anemia, thrombocytopenia, leukopenia, B and T cell abnormalities, antinuclear antibodies, cryoglobulins, rheumatoid factors, false-positive serological test results for syphilis, alterations in serum complement, and immunological abnormalities. The diseases usually included in this category are mixed connective tissue disease, necrotizing vasculitis, and other vasculopathies; polymyositis; relapsing polychondritis; rheumatic fever; rheumatoid arthritis; scleroderma; and systemic lupus erythematosus. The cause of most of these diseases is unknown. Hereditary factors and deficiencies, autoimmunity, environmental antigens, infections, allergies, and antigen-antibody complexes in various combinations are probably involved. Also called connective tissue disease.
connective tissue disease; collagen vascular disease group of autoimmune conditions characterized by variable presentations of a range of systemic inflammatory and immunological features, i.e. vasculitis, Raynaud's disease, calcinosis, oesophagitis, sclerodactyly and telangiectasia; e.g. systemic lupus erythematosus, progressive systemic sclerosis; scleroderma, rheumatoid arthritis, polyarteritis nodosa and dermatomyosotis
References in periodicals archive ?
Periorbital and/or peripheral oedema, pallor, gouty tophi, arthritis, signs of collagen vascular disease and macroglossia (amyloidosis).
of Age, Range Male/Female Patients (Mean), y AINOS (a) 24 31-84 (61) 7/17 Polymyositis/dermatomyositis 7 33-66 (49) 2/5 Rheumatoid arthritis 38 25-82 (61) 9/29 Scleroderma 2 53-75 (64) 0/2 Systemic lupus erythematosus 25 23-72 (49) 3/22 Vasculitis 6 40-80 (56) 2/4 Control group 38 26-82 (58) 12/26 Abbreviations: AINOS, autoimmune disease, not otherwise specified; CVD, collagen vascular disease.
There are many different approaches to the evaluation of the lungs in patients with collagen vascular diseases.
The presence of a previously undiagnosed collagen vascular disease can be suggested by a history of arthralgias, myalgias, arthritis, muscle weakness or skin rashes.
The Rheumatology Division at Johns Hopkins University is home to one of the nation's premier groups of investigators in collagen vascular diseases, with experts in vasculitis, lupus, rheumatoid arthritis, scleroderma and other conditions.
Coverage includes the normal physiologic changes that occur during pregnancy, including a chapter on high altitude, chronic hypoxia, and pregnancy; general management principles, such as diagnostic imaging and prescribing in pregnancy; and discussion of specific pulmonary disorders and issues--obstructive sleep apnea, restless legs syndrome and periodic limb movement disorder, asthma, tuberculosis, pneumonia, chronic pulmonary disease, neuromuscular and chest wall diseases, cystic fibrosis, collagen vascular disease, venous thromboembolism, pulmonary arterial hypertension, acute lung injury, and airway management and mechanical ventilation.
Effusions secondary to Collagen Vascular Disease -Effusions secondary to rheumatoid arthritis are predominantly mononuclear cell exudates, typically with low glucose levels (< 10 mg/dl), high titers of rheumatoid factor (> 640) and cloudy appearance (pseudochylous or cholesterol effusions).
The exception is Candida onycholysis, which occurs in women who have Raynaud's syndrome and other patients with collagen vascular disease.
Extensive workup for collagen vascular disease and infectious pathology were negative.
The primary differential diagnoses include Wegener's granulomatosis, sinonasal lymphomas and other primary neoplasms of the paranasal sinuses, collagen vascular disease, and sinusitis with osteitis secondary to cocaine use.
Some of the indications for preterm antepartum monitoring include disorders of growth; multiple gestation with discordancy; and maternal medical conditions such as hypertension, collagen vascular disease, and preexisting and gestational diabetes.
STRIDE II is a 240 patient trial including patients with WHO Class II-IV PAH of primary or secondary etiologies (due to collagen vascular disease or certain congenital heart defects) with an entry six-minute walk distance of less than or equal to 450 meters.