collagen disease


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Related to collagen disease: Scleroderma, Connective tissue disorder

col·la·gen dis·ease

, collagen-vascular disease
a group of generalized diseases affecting connective tissue and frequently characterized by fibrinoid necrosis or vasculitis; in some collagen diseases, auto-immunization, particularly antinuclear antibodies, has been shown and circulating immune complexes are found. The term is not entirely acceptable because there is no evidence that collagen is primarily involved; "collagen" was once synonymous with "connective tissue" rather than describing a specific fibrinous protein in that tissue.
See also: connective-tissue disease.

collagen disease

an abnormal condition characterized by extensive disruption of the connective tissue, often involving inflammation and fibrinoid degeneration. Collagen diseases include polyarteritis nodosa, systemic lupus erythematosus, osteoarthritis, and rheumatoid arthritis. See also collagen vascular disease.

col·la·gen dis·ease

, collagen-vascular disease (kol'ă-jen di-zēz', kol'ă-jen-vas'kyū-lăr)
A group of generalized diseases affecting connective tissue and frequently characterized by fibrinoid necrosis or vasculitis; in some collagen diseases, autoimmunization, particularly antinuclear antibodies, has been shown and circulating immune complexes are found. The term is not entirely acceptable because there is no evidence that collagen is primarily involved; "collagen" was once synonymous with "connective tissue" rather than describing a specific protein in that tissue.
See also: connective-tissue disease

collagen disease

A term formerly, and erroneously, applied to such conditions as rheumatic fever, ankylosing spondylitis, polyarteritis nodosa, lupus erythematosus, rheumatoid arthritis and dermatomyositis but now applied to those known to be caused by defects in the chemical structure of collagen and its distribution and quantity. The collagen diseases include solar and senile elastosis, SCURVY, STRIAE, KELOIDS, PEYRONIE'S DISEASE, PSEUDOXANTHOMA ELASTICUM and the EHLERS-DANLOS SYNDROME.

col·la·gen dis·ease

, collagen-vascular disease (kol'ă-jen di-zēz', kol'ă-jen-vas'kyū-lăr)
Generalized disorder affecting connective tissue.
References in periodicals archive ?
This lady also had a significant peripheral eosinophilia unresponsive to anti parasitic chemotherapy, a normal bone marrow biopsy aspirate and p-ANCA, which was non reactive thus ruling out parasitic infestations, collagen diseases such as Churgh-Strauss Syndrome and haematological malignancies.
OTC Bulletin Board: LANN), a manufacturer of pharmaceutical products, announced that the Food and Drug Administration has approved the reformulated version of its existing abbreviated new drug application ("ANDA") for Prednisolone Tablets USP, 5 mg, indicated for the anti-inflammatory treatment caused by organ disorders, including endocrine, rheumatic, collagen diseases like lupus, dermatologic diseases, ophthalmic diseases, respiratory diseases, gastrointestinal diseases, neoplastic diseases, and meningitis.