12-14) The "target" sign can also be seen in patients with IBD, other infectious colitides, vascular disorders, and patients with portal hypertension.
Despite diagnostic technologic advances, CMV remains an elusive mimicker of colitides, and thus always needs to be a consideration in overall clinical decision making.
difficile-associated colitis, ischaemic colitis, bacterial and viral colitides
, parasitosis and surgical pathologies should be differentiated.
It was originally felt to be a specific CT finding for Clostridium difficile-induced pseudomembranous colitis, but it has also been described with colitides
of differing etiologies.
Gastral antral biopsy in the differentiation of pediatric colitides
Pseudomembranous colitis is a descriptive term for colitides defined by the presence of pseudomembranes on the colonic or, rarely, small intestinal mucosa.
Histologically, drug-induced colonic injury is often nonspecific and may mimic many types of colitides, including IBD, microscopic colitis, ischemic colitis, or GVHD.
However, indolent colitides
caused by infectious agents, such as Entamoeba histolytica and intestinal tuberculosis (ITB), may resemble IBD by their well-developed chronicity and granuloma (in ITB).
The majority of infectious colitides
are never biopsied, as the patient's symptoms often resolve before the patient has time to see a gastroenterologist.
1) Joel Greenson, MD, professor of pathology at the University of Michigan and past president of the Gastrointestinal Pathology Society, focused on the evolving role of diagnostic pathologists in managing patients with an increasingly complex array of colitides