colistimethate sodium

co·lis·ti·meth·ate so·di·um

(kō-lis'ti-meth'āte sō'dē-ŭm),

Contains the pentasodium salt of the penta(methanesulfonic acid) derivative of colistin A as the major component, with a small proportion of the pentasodium salt of the same derivative of colistin B; an effective antibiotic against most gram-negative bacilli (except Proteus), given intramuscularly.
See also: polymyxin.

Synonym(s): cholistine sulphomethate sodium

colistimethate sodium

[kō′listim′əthāt]

an antibiotic. Also called colistin sulfomethate sodium.

indications It is prescribed in the treatment of GI infections caused by certain gram-negative microorganisms and as a topical medication.

contraindications Known hypersensitivity to this drug prohibits its use.

adverse effects Among the more serious adverse reactions are nephrotoxicity and neurotoxicity.

co·lis·ti·meth·ate so·di·um

(kō-lis'ti-meth'āte sō'dē-ŭm)

Effective antibiotic against most gram-negative bacilli (except Proteus), given intramuscularly.

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References in periodicals archive ?

4 Colistimethate Sodium (nebulized; numerous generic names) 53

Table 12: Product Profile - Colistimethate Sodium 54

OpportunityAnalyzer: Cystic Fibrosis - Opportunity Analysis and Forecasts to 2018 - Event-Driven Update

An additional problem is that prescribing units differ between manufacturers, including mg for colistin base activity (CBA) and colistimethate sodium (CMS), and international units for CMS.

Systematic review of the evidence for rational dosing of colistin

NYSE: FRX), an international pharmaceutical manufacturer and marketer, today announced that it has been granted European Medicines Agency (EMA) approval to market Colobreathe dry powder colistimethate sodium for inhalation for treating cystic fibrosis patients aged 6 years and older with chronic lung infection caused by P.

In 2011 Forest Laboratories acquired all rights held by Gruenenthal to colistimethate sodium in several European countries and also reacquired rights to Colobreathe previously licensed from Forest.

Colobreathe is a capsule containing 1,662,500 IU of colistimethate sodium which is approximately equal to 125 mg.

Forest Laboratories Receives European Marketing Approval for Colobreathe[R] Dry Powder Inhaler

LONDON, September 15 /PRNewswire/ -- Forest Laboratories UK Ltd, (a wholly owned subsidiary of Forest Laboratories Inc) announced that following the successful completion of its pan-European multi-centre phase III study (the Freedom Study), it has applied to the European Medicines Evaluation Agency (EMEA) to licence its new formulation dry powder colistimethate sodium for inhalation (Colobreathe(R)) for use by Cystic Fibrosis patients.

Forest Laboratories UK Ltd Submits Marketing Authorisation Application for the First Dry Powder Inhalation Antibiotic for Cystic Fibrosis Patients

Colistimethate Sodium 1Million Iu, Powder For Solution For Injection In 10Ml Vial

Inj. colistimethate sodium 1million iu, powder for solution for injection in 10ml vial

Objective: Colistimethate Sodium (CMS hereinafter) is a rapidly bactericidal antimicrobial agent with a significant post-antibiotic effect against multidrug resistant Gram-negative pathogens.

PROTOCOL: New processing technology for colistmethate sodium, leading to improved and cost-effective formulations for pharmaceutical and veterinary markets

Framework agreement with a single operator per lot for provision of medicines Ertapenem (DOE), colistimethate sodium (DOE), Tirofiban (DOE), Cefepime (DOE), imipenem / cilastatin (DOE) and Antiretrovirals in combination lamivudine (DOE) / Zidovudine (DOE).

Provision of Pharmaceutical products

5% (hydrocortisone cream, USP), ANUSOL-HC 25-mg SUPPOSITORY (hydrocortisone acetate) and COLY-MYCIN(R)-M PARENTERAL (sterile colistimethate sodium, USP) and certain manufacturing contracts with third parties from Warner-Lambert Company in February 1998, and the sales growth of certain significant branded pharmaceutical products, including in particular the CORTISPORIN(R) product line.