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colfosceril

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colfosceril /col·fos·e·ril/ (kol-fos´ĕ-ril) a synthetic pulmonary surfactant used as the palmitate ester, in combination with cetyl alcohol and tyloxapol, in the prophylaxis and treatment of neonatal respiratory distress syndrome.
colfosceril
[kolfos′eril]
a synthetic pulmonary surfactant used as the palmitate ester in combination with tyloxapol and as an alcohol in prophylaxis and treatment of neonatal respiratory distress syndrome, instilled into the endotracheal tube for intratracheal administration.

colfosceril [kol-fos´ĕ-ril]
a synthetic pulmonary surfactant used as the palmitate ester in combination with tyloxapol and an alcohol in prophylaxis and treatment of neonatal respiratory distress syndrome; instilled into the endotracheal tube for intratracheal administration.


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It is a natural bovine lung extract mixed with colfosceril palmitate (DPPC), palmitic acid, and tripalmitin.
Lucinactant Comparison Trial to Colfosceril palmitate and Beractant In 2005, Moya et al published a large prospective randomized clinical trial that reported a higher RDS mortality rate for colfosceril palmitate (a synthetic surfactant) and beractant (a natural surfactant) than for lucinactant.
 
 
 
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