cold knife conization

cold knife con·i·za·tion

obtaining a cone of endocervical tissue with a cold knife blade so as to preserve histologic characteristics and avoid desiccating tissue.
The excision of a conical piece of uterine cervix to confirm the Dx of HPV, CIN or cancer based on the results of a pap smear, and to treat same, since the pathology is usually confined to the cone

cold knife co·ni·za·tion

(kōld nīf kon'i-zā'shŭn)
Obtaining a cone of endocervical tissue with a cold knife blade so as to preserve histologic characteristics and avoid desiccating tissue.
References in periodicals archive ?
Excision methods include cold knife conization (CKC), loop electrosurgical excision procedure (LEEP), or laser.
It may be considered as a suitable alternative to cold knife conization or hysterectomy for younger females who are yet to complete their families.
The physician decided to do a cold knife conization to rule out a more severe lesion.
A recent meta-analysis of 27 controlled cohort studies found that cold knife conization and LEEP were associated with increased obstetrical risks, such as delivery at less than 37 weeks' gestation and a birth weight <2500 g (TABLE 2).
Further, the use of neoadjuvant chemotherapy followed by cold knife conization for fertility preservation in women with larger tumors has been proposed.
A comparison between loop electrosurgical excision procedure and cold knife conization for treatment of cervical dysplasia: residual disease in a subsequent hysterectomy specimen.
Referral for cold knife conization was limited to patients with glandular atypia on biopsy or endocervical curretage, or colposcopic impression of glandualr atypia.
One study found microfibrillar collagen (MC) use during cold knife conization resulted in nonsignificant reduction in operative time and similar hemostatic results compared to Sturmdorf suture (Obstet.
Based on prior studies of pregnant patients who had undergone cold knife conization, complications do not occur until there is considerably greater cervical tissue excision than that which occurs in clectrosurgical loop excisions.
Today, we have myriad tools to detect and treat cervical cancer, from Pap smears to colposcopies, and from directed biopsy to laser and electrosurgical therapies to cold knife conization.
A randomized trial comparing two methods of cold knife conization with laser surgery.