cold hemagglutinin disease

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Related to cold hemagglutinin disease: warm agglutinin disease, cold antibody

cold he·mag·glu·ti·nin dis·ease

a condition associated with the presence of hemagglutinating autoantibody active in vivo, but in vitro particularly or solely active in the cold; when the concentration of IgM antibody is high there may be increased serum viscosity, but clinical manifestations (due to hemagglutination) usually appear following exposure to cold; hemolysis usually is mild but may be severe, resulting in autoimmune hemolytic anemia, cold antibody type.


1. an acute disease of the upper respiratory tract characterized by cough, sneezing, running at the eyes and nose and mild fever, similar to the common cold of humans, occurring in captive primates.
2. a relatively low temperature; the lack of heat. A total absence of heat is absolute zero, at which all molecular motion ceases. See also hypothermia.

cold acclimation
short-term adjustments to carbohydrate and fat metabolism in response to exposure to low environmental temperatures.
cold acclimatization
heat production is not increased, but heat loss is reduced by changes in haircoat and vascular supply to the skin.
cold applications
the primary effect of cold on the surface of the body is constriction of the blood vessels. Cold also causes contraction of the involuntary muscles of the skin. These actions result in a reduced blood supply to the skin and produce a marked pallor. If cold is prolonged there may be damage to the tissues because of the decreased blood supply.
The secondary effects of cold are the opposite of its primary action. There is increased cell activity, dilatation of the blood vessels, and increased sensitivity of the nerve endings.
cold barn
see cold housing (below).
cold cow syndrome
see shock.
a procedure that promotes growth of some bacteria during laboratory isolation. Suspensions of specimens are held at refrigerator temperatures for extended periods before being cultured. Recommended for recovery of Listeria monocytogenes from neural listeriosis and Yersinia spp.
cold exposure
cold hemagglutinin disease
see cold agglutinin disease.
cold housing
thin-walled, uninsulated barns with no central heating.
cold injury
includes hypothermia and frostbite.
refers to a hound which is able to follow a cold (very old) scent.
cold receptors
receptors in the skin which are sensitive to low temperatures.
cold rooms
walk-in refrigerator; temperature used varies with material stored, e.g. meat needs 32°F to 45°F (0°C to 7°C), offal needs less than 28°F (−2°C).
fitting a horseshoe without heating it in a forge and shaping it exactly to the foot. See also shoeing.
cold shortening
shrinkage of meat when temperature is excessively low in early stages of chilling.
cold steel surgery
that using unheated cutting instruments; the normal surgical procedure in contrast to electrosurgery or cryosurgery.
cold storage
for meat to be stored for more than 72 hours the chilling temperature should be between 30°F and 23°F (−1 and −5°C) and the humidity less than 90%.
cold store taint
cut lean surfaces of chilled meat are covered with a brown slime and have a sour smell caused by growth of the bacteria Achromobacter spp.
cold stress
occurs at temperatures less than 50°F (10°C), varying with chill factor, wetness, protection from wind.
cold therapy
see cryosurgery, therapeutic hypothermia.
cold tray
the container used for immersion of instruments in a cold sterilization solution, usually with a rack that allows instruments to be lifted above the fluid level to drain before use.
cold water hemolytic anemia
see cold anemia.