colchicine myopathy and neuromyopathy

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colchicine myopathy and neuromyopathy

A complication of colchicine use, which is characterised by proximal muscle weakness, spontaneous activity by EMG of proximal muscles, axonal polyneuropathy, and increased creatine kinase.

EEG
Abnormal spontaneous activity.
References in periodicals archive ?
23) Colchicine myopathy is believed to result from an inhibition of tubulin polymerization into microtubules, as well as alteration in the expression of dopaminergic receptors.