coenzyme Q10


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coenzyme Q10

A factor present in mitochondria which extracts energy from foods. It has acquired a reputation among fringe nutritionists as being effective in detoxifying patients with an overdose of environmental pollutants; it is also claimed to be beneficial in treating hypertension, obesity, periodontal disease, preventing cancer, increasing longevity and revitalising the immune system.

coenzyme

(ko-en'zim?) [ co- + enzyme]
An enzyme activator; a diffusible, heat-stable substance of low molecular weight that, when combined with an inactive protein called apoenzyme, forms an active compound or a complete enzyme called a holoenzyme (e.g., adenylic acid, riboflavin, and coenzymes I and II).

coenzyme A

A derivative of pantothenic acid, important as a carrier molecule for acetyl groups in many reactions including the Krebs cycle (tricarboxylic acid cycle) and the oxidation of fatty acids.

coenzyme Q

A dietary supplement promoted by alternative medicine practitioners as an antioxidant and as a treatment for gingivitis and heart diseases.

coenzyme Q10

Ubiquinone.

coenzyme Q10

also known as ubiquinone, a non-essential lipid-soluble nutrient found predominantly in animal foods and at low levels in plant foods. In the body it is located primarily in the mitochondria, especially in skeletal and cardiac muscle. As a component of the electron transport chain, it is important for ATP formation. It is also believed to have an antioxidant function, protecting DNA and cell membranes from oxidative damage. For athletes, coenzyme Q10 supplements are claimed to enhance energy production through the electron transport chain, and to reduce the oxidative damage of exercise. Research does not support the claim, reporting either no effect or in some cases an ergolytic rather than ergogenic effect. See also ergogenic aids; appendix 4.4 .

coenzyme Q,

n an enzyme along the electron transport chain. Scientific name: 2,3 dimethoxy-5 methyl-6-decaprenyl benzoquinone; uses: heart disease—including ischemic heart disease, dysrhythmias, congestive heart failure, hypertension, angina pectoris, mitral valve prolapse—diabetes, infertility, Bell's palsy, periodontal disease; precautions: pregnancy, lactation, children; can cause nausea, diarrhea, epigastric pain. Also called
Co-Q10, mitoquinone, ubidecarenone, and
ubiquinone.
References in periodicals archive ?
Tolerance of high-dose (3,000 mg/day) coenzyme Q10 in ALS.
Greenberg S ve Frishman WH, 1990, Coenzyme Q10 : a new drug for cardiovascular disease.
Coenzyme Q10 may inhibit the peroxidation of lipids, thus acting as an antioxidant and protects tissue against oxidative injury.
Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes.
Coenzyme Q10 has been and continues to be used clinically in all these areas.
Coenzyme Q10 is a vitamin-like substance, a powerful antioxidant and moisturiser which works by speeding up cell repair.
The study indicated that Coenzyme Q10 and Ginkgo biloba do not influence the clinical effect of warfarin.
If coenzyme Q10 does work, you may need to get your other medications for hypertension decreased, but that would be at the discretion of your physician," Dr.
The fine chemicals business of Asahi Kasei Pharma, which performs the production and sale of coenzyme Q10, has thus been placed in a position of continuing unprofitability.
Consult your doctor before taking coenzyme Q10 or any supplement, because it could interfere with your prescription medications.
Coenzyme Q10 is a vitamin-like substance that plays a central role in the body's energy production.