coenzyme Q10

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coenzyme Q10

A factor present in mitochondria which extracts energy from foods. It has acquired a reputation among fringe nutritionists as being effective in detoxifying patients with an overdose of environmental pollutants; it is also claimed to be beneficial in treating hypertension, obesity, periodontal disease, preventing cancer, increasing longevity and revitalising the immune system.


(ko-en'zim?) [ co- + enzyme]
An enzyme activator; a diffusible, heat-stable substance of low molecular weight that, when combined with an inactive protein called apoenzyme, forms an active compound or a complete enzyme called a holoenzyme (e.g., adenylic acid, riboflavin, and coenzymes I and II).

coenzyme A

A derivative of pantothenic acid, important as a carrier molecule for acetyl groups in many reactions including the Krebs cycle (tricarboxylic acid cycle) and the oxidation of fatty acids.

coenzyme Q

A dietary supplement promoted by alternative medicine practitioners as an antioxidant and as a treatment for gingivitis and heart diseases.

coenzyme Q10


coenzyme Q10

also known as ubiquinone, a non-essential lipid-soluble nutrient found predominantly in animal foods and at low levels in plant foods. In the body it is located primarily in the mitochondria, especially in skeletal and cardiac muscle. As a component of the electron transport chain, it is important for ATP formation. It is also believed to have an antioxidant function, protecting DNA and cell membranes from oxidative damage. For athletes, coenzyme Q10 supplements are claimed to enhance energy production through the electron transport chain, and to reduce the oxidative damage of exercise. Research does not support the claim, reporting either no effect or in some cases an ergolytic rather than ergogenic effect. See also ergogenic aids; appendix 4.4 .

coenzyme Q,

n an enzyme along the electron transport chain. Scientific name: 2,3 dimethoxy-5 methyl-6-decaprenyl benzoquinone; uses: heart disease—including ischemic heart disease, dysrhythmias, congestive heart failure, hypertension, angina pectoris, mitral valve prolapse—diabetes, infertility, Bell's palsy, periodontal disease; precautions: pregnancy, lactation, children; can cause nausea, diarrhea, epigastric pain. Also called
Co-Q10, mitoquinone, ubidecarenone, and
References in periodicals archive ?
The efficacy and safety of coenzyme Q10 has been extensively documented, with more than 1,000 research papers, including more than 100 published randomised controlled clinical trials.
Oral administration of Coenzyme Q10 has also provided beneficial effects on periodontal tissue.
Each capsule of Pharma Nord Bio-Quinone Q10 contains coenzyme Q10 in a highly absorbed, patented oil-based delivery system.
Another news item concerns Coenzyme Q10 or Ubiquinone.
The dietary supplement coenzyme Q10 is being studied for use in migraine prophylaxis, based on the hypothesis that mitochondrial dysfunction may be involved in the pathogenesis of the disorder.
The evidence: No studies have looked at whether coenzyme Q10 can help prevent diabetes.
The dietary supplement coenzyme Q10 has shown some promise in the treatment of early Parkinson's disease, Huntington's disease, and as migraine prophylaxis.
Also new is the reformulated Nivea Visage Q10 Plus Wrinkle Control skin care line with naturally-occurring skin components, coenzyme Q10 and coenzyme biotin, to repair the skin and reduce wrinkles with little irritation.
Several years ago, DiMauro, a neurologist at Columbia University College of Physicians and Surgeons in New York, had noticed that muscle tissue from a patient with familial cerebellar ataxia had a deficiency in a compound called coenzyme Q10 (CoQ10).
In addition to basic toothpaste ingredients, Q-Dent contains an antioxidant known as coenzyme Q10, or CoQ10.
was awarded United States Patent 6,056,971 for the Bio-Solv process used to enhance the bioavailability and absorption of Coenzyme Q10.