coenzyme A

coenzyme /co·en·zyme/ (ko-en´zīm) an organic nonprotein molecule, frequently a phosphorylated derivative of a water-soluble vitamin, that binds with the protein molecule (apoenzyme) to form the active enzyme (holoenzyme).

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coenzyme A  a coenzyme containing among its constituents pantothenic acid and a terminal thiol group that forms high-energy thioester linkages with various acids, e.g., acetic acid (acetyl CoA) and fatty acids (acyl CoA); these thioesters play a central role in the tricarboxylic acid cycle, the transfer of acetyl groups, and the oxidation of fatty acids. Abbreviated CoA and CoA-SH.

coenzyme Q , coenzyme Q10 ubiquinone.

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coenzyme A

n. Abbr. CoA

A coenzyme present in all living cells that functions as an acyl group carrier and is necessary for fatty acid synthesis and oxidation, pyruvate oxidation, and other acetylation.

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coenzyme A (CoA)

Etymology: L, cum + en, into, zyme, ferment

an important metabolite in the citric acid cycle. Although not a true enzyme, it plays a significant role in the transfer of acetyl groups and the metabolism of acids and amino acids.

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coenzyme A (CoA),

n an important metabolite in the citric acid cycle. Although not a true enzyme, it plays a significant role in the transfer of acetyl groups and the metabolism of acids and amino acids.

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coenzyme

an organic molecule, usually containing phosphorus and some vitamins, often separable from the enzyme protein but essential as a cosubstrate in catalysis; a coenzyme and an apoenzyme must unite in order to function (as a holoenzyme).

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coenzyme A

essential for carbohydrate and fat metabolism; among its constituents are pantothenic acid and a terminal SH group, which forms thioester linkages with various acids, e.g. acetic acid (acetyl-CoA) and fatty acids (acyl-CoA); abbreviated CoA.

coenzyme A acetoacetyl

see acetoacetyl coa.

coenzyme A acetyl

see acetyl coa.

coenzyme Q

any of a group of related quinones with isoprenoid units in the side chains (the ubiquinones), occurring in the lipid fraction of mitochondria and serving, along with the cytochromes, as an intermediate in electron transport; they are similar in structure to vitamin K₁.

coenzyme R

see biotin.