codeine phosphate


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co·deine phos·phate

a water-soluble salt of codeine often used in the pharmaceutical preparation of liquid medications containing codeine.

codeine phosphate

an opioid analgesic and antitussive.
indications It is prescribed to suppress cough and to relieve mild to moderate pain.
contraindication Known hypersensitivity to opiates is the only contraindication.
adverse effects Among the more serious adverse reactions are depression of the central nervous system, paradoxic excitement, and drug dependence.

codeine phosphate

The phosphate of the alkaloid codeine; used because of its free solubility in water.
See also: codeine

codeine phosphate

narcotic opioid analgesic derived from morphine, used to control pain; also formulated with paracetamol (e.g. 30 mg codeine phosphate and 500 mg paracetamol tablets; Table 1); regular use predisposes to constipation; overdose suppresses both respiration and cough reflex, and can cause death
Table 1: Analgesic codeine preparations
AgentConstituents
Co-codamol(8/500) 8 mg codeine phosphate; 500 mg paracetamol
(15/500) 15 mg codeine phosphate; 500 mg paracetamol
(30/500) 30 mg codeine phosphate; 500 mg paracetamol
Co-dydramol(10/500) 10 mg dihydrocodeine tartrate; 500 mg paracetamol
Co-proxamol(32.5/325) 32.5 mg dextropropoxyphene hydrochloride; 325 mg paracetamol

Note: co-proxamol withdrawn in UK, due to adverse links to heart failure and respiratory depression

References in periodicals archive ?
You further admitted to having taken codeine phosphate on other occasions.
Concentration ratios of codeine-tomorphine in plasma after a single oral dose (100 mg) of codeine phosphate.
Both in the cases of codeine phosphate and extract of Trichodesma indicum (at different doses), the maximum inhibition of cough reflex observed at 90 min after drug administration.
e report said: "You told the panel that you were now a very dierent person to the one who stole the codeine phosphate.
Plasma codeine and morphine concentrations after a single oral dose of codeine phosphate.
In the time that I have been nursing neuroscience patients I was always taught to give codeine phosphate for pain relief so as not to mask any neurological deterioration.
Average daily doses of approximately 250mg of tramadol in divided doses were generally comparable to five doses of acetaminophen 300mg with codeine phosphate 30mg daily, five doses of aspirin 325mg with codeine phosphate 30mg daily, or two to three doses of acetaminophen 500mg with oxycodone hydrochloride 5mg daily.
Both the two products complement Akorn's current promethazine formulations which cover promethazine HCl oral solution, USP; promethazine HCl and codeine phosphate syrup CV; and promethazine HCl and dextromethorphan HCl oral solution.
Staff spotted the prescription was not stamped and Swanston - who filled out the form in her grandad's car - had spelled Codeine Phosphate incorrectly.
Some of her mum's old medication, a pack of painkilling codeine phosphate, was also found by her side.
The court heard earlier that matters came to light last March when a hospital cleaner discovered six empty packets of codeine phosphate in a bin.
Mr Richings said: "She gave a false address but was prescribed diazepam and the same day she phoned again and was prescribed codeine phosphate.