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a water-soluble salt of codeine often used in the pharmaceutical preparation of liquid medications containing codeine.
an opioid analgesic and antitussive.
indications It is prescribed to suppress cough and to relieve mild to moderate pain.
contraindication Known hypersensitivity to opiates is the only contraindication.
adverse effects Among the more serious adverse reactions are depression of the central nervous system, paradoxic excitement, and drug dependence.
The phosphate of the alkaloid codeine; used because of its free solubility in water.
See also: codeine
codeine phosphatenarcotic opioid analgesic derived from morphine, used to control pain; also formulated with paracetamol (e.g. 30 mg codeine phosphate and 500 mg paracetamol tablets; Table 1); regular use predisposes to constipation; overdose suppresses both respiration and cough reflex, and can cause death
|Co-codamol||(8/500) 8 mg codeine phosphate; 500 mg paracetamol|
(15/500) 15 mg codeine phosphate; 500 mg paracetamol
(30/500) 30 mg codeine phosphate; 500 mg paracetamol
|Co-dydramol||(10/500) 10 mg dihydrocodeine tartrate; 500 mg paracetamol|
|Co-proxamol||(32.5/325) 32.5 mg dextropropoxyphene hydrochloride; 325 mg paracetamol|
Note: co-proxamol withdrawn in UK, due to adverse links to heart failure and respiratory depression