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cocarcinogenesis |
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cocarcinogenesis /co·car·ci·no·gen·e·sis/ (ko-kahr″sĭ-no-jen´ĕ-sis) the development, according to one theory, of cancer only in preconditioned cells as a result of conditions favorable to its growth. cocarcinogenesis the development, according to one theory, of cancer only in preconditioned cells as a result of conditions favorable to its growth. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Proposed mechanisms include genotoxicity, oxidative stress, inhibition of DNA repair, tumor promotion, cocarcinogenesis, cell proliferation, and altered signal transduction or DNA methylation (Hughes 2002; Kitchin 2001; Rossman 2003). The mechanism(s) by which arsenic exposure contributes to human cancer risk is unknown; however, several indirect cocarcinogenesis mechanisms have been proposed. |
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