cocaine hydrochloride

cocaine hydrochloride

a water-soluble salt used for local anesthesia of the eye or mucous membranes.

cocaine hydrochloride

a white crystalline powder used as a local anesthetic. It was originally derived from coca leaves but can also be prepared synthetically. Cocaine is a Schedule I drug under the Controlled Substances Act of 1970.
indications In solution it is sometimes used as a topical anesthetic applied to mucous membranes. Its vasoconstrictive action slows bleeding and limits absorption. Prolonged or frequent use may damage the mucous membranes.
contraindications It is incompatible with all alkaloid precipitants, mercurials, and silver nitrate. Central nervous system overstimulation may result from use with monoamine oxidase inhibitors, amphetamines, or guanethidine. Combination with epinephrine or norepinephrine can lead to cardiac arrhythmias or ventricular fibrillation. Persons with severe cardiovascular disease, thyrotoxicosis, hypotension, or hypertension should not take this drug.
adverse reactions Among the most serious adverse reactions are excitement, depression, euphoria, restlessness, tremors, vertigo, nausea, vomiting, hypotension, hypertension, abdominal cramps, exophthalmia, mydriasis, peripheral vascular collapse, tachypnea, tachycardia, chills, fever, coma, and death from respiratory failure.
note Cocaine hydrochloride solution should be freshly made; it deteriorates rapidly on standing and cannot be heat-sterilized.
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Effect of cocaine on neurotransmission

co·caine hy·dro·chlo·ride

(kō-kān' hī'drō-klōr'īd)
A water-soluble salt used for local anesthesia of the eye or mucous membranes.

co·caine hy·dro·chlo·ride

(kō-kān' hī'drō-klōr'īd)
Water-soluble salt used for local anesthesia of the eye or mucous membranes.
References in periodicals archive ?
Noe Juarez was charged with conspiracy to distribute more than five kilograms of cocaine hydrochloride, or crack cocaine, in Louisiana.
The FELCN reported destroying 74 cocaine hydrochloride processing labs and 5,306 rustic cocaine labs during 2014, a nine percent increase and 10 percent decrease from 2013, respectively.
Compared to 2012, seizures of coca leaf decreased by 36 per cent to 476 tons, cocaine base paste by 37 per cent to 20 tons, and cocaine hydrochloride by 62 per cent to 1.
The Incomplete Truth, 2006, a dove in formaldehyde, is as good a sculptural representation of a cocaine hydrochloride high as could be made; an orgasm substitute set within a quivering void (sexuality is conspicuously absent in Hirst's work).
Most important, anti-drug forces seized 12 tons of cocaine in 2006 in contrast to just three tons in 2005; 26% more cocaine base and cocaine hydrochloride than during the first nine months of 2005, and eradicated 5,000 hectares of illegal coca fields.
Cocaine may be obtained as the water-soluble crystalline salt, cocaine hydrochloride (can be used medicinally as a local anaesthetic), or as the free cocaine base in powder or pellet (crack) form.
Chemicals, solvents, and increasingly sophisticated equipment convert the leaves first to coca paste, then to cocaine base, and finally to cocaine hydrochloride.
After she was sedated and intubated, 4% topical cocaine hydrochloride was applied intranasally for local vasoconstriction and anesthesia.
CRACK cocaine is the Class A drug cocaine hydrochloride, chemically altered to form crystals or "rocks".
Over 170 metric tons of cocaine were interdicted in Colombia and at sea, and more that 200 cocaine hydrochloride labs destroyed during 2004.
Cocaine is a white powder, whereas Crack is Cocaine Hydrochloride, which has been chemically altered to form crystals that can be smoked