cobalamin


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.
Related to cobalamin: folic acid, vitamin B12, cobalamin deficiency, Methylcobalamin

cobalamin

 [ko-bal´ah-min]
a cobalt-containing complex common to all members of the vitamin B12 group; see also vitamin.

co·bal·a·min (Cbl),

(kō-bal'ă-min),
General term for compounds containing the dimethylbenzimidazolylcobamide nucleus of vitamin B12.

cobalamin

/co·bal·a·min/ (ko-bal´ah-min) a compound comprising the substituted ring and nucleotide structure characteristic of vitamin B12, either one lacking a ligand at the 6 position of cobalt or any substituted derivative, including cyanocobalamin, particularly one with vitamin B12 activity.

cobalamin

(kō-băl′ə-mĭn) also

cobalamine

(-mēn′)

cobalamin

[kōbôl′əmin]
Etymology: Ger, kobold, mine goblin
a generic term for a chemical portion of the vitamin B12 molecule. See also cyanocobalamin.

co·bal·a·min

(kō-bal'ă-min)
General term for compounds containing the dimethylbenzimidazolylcobamide nucleus of vitamin B12.

cobalamin,

n See vitamin B12.

co·bal·a·min

(kō-bal'ă-min)
General term for compounds containing the dimethylbenzimidazolylcobamide nucleus of vitamin B12.

cobalamin,

cobalamin, cobalamine

a cobalt-containing complex common to all members of the vitamin B12 group.
References in periodicals archive ?
12] analogs, whereas HC binds cobalamin and the analogs equally well (2).
However, cobalamin and the remaining ascorbate would both arrive in the interstitial fluid.
The concurrent decrease in both cobalamin and folate and increase in tHcy observed during adolescence may reflect the abstraction of these nutrients from serum to support growth and consequent accumulation of tHcy when folate and/or cobalamin concentrations are insufficient to support its remethylation (23).
Alzheimer disease is often accompanied by unexplained low cobalamin levels.
If lactating mothers are cobalamin deficient, their infants should be evaluated for cobalamin deficiency and treated appropriately, the researchers recommended.
These statements include those relating to: our cash burn rate, clinical trial plans and timelines and clinical results for MuGard and Cobalamin, our ability to achieve clinical and commercial success and our ability to successfully develop marketed products.
Cobalamin was given at a dose of 1000 [micro]g per day with intramuscular injection (week 1), 1000, [micro]g twice weekly (week 2), 1000, [micro]g/week for the third and fourth weeks, and then 1000, [micro]g/ month.
HEMATOLOGICAL RESPONSE TO SHORT-TERM ORAL CYANOCOBALAMIN THERAPY FOR THE TREATMENT OF COBALAMIN DEFICIENCIES IN ELDERLY PATIENTS.
OBJECTIVE: We examined the associations between plasma cobalamin and uAs metabolites.
3), (5), (12) In fact, the relationship between vitamin B12 deficiency and elevated homocysteine levels is now believed to be so intimate that a recent recommendation for evaluating vitamin B12 deficiency is to determine the serum cobalamin level as a screening test and, if it is low, to determine either serum or urine homocysteine levels, as well as methylmalonic acid levels, for confirmation.
Type I antibodies block the cobalamin binding site on the intrinsic factor molecule, preventing uptake of the vitamin.