coagulase /co·ag·u·lase/ (-lās) an antigenic substance of bacterial origin, produced by staphylococci, which may be causally related to thrombus formation.
coagulase
co·ag·u·lase (k - g y -l s , -lz)n. An enzyme, such as rennin or thrombin, that induces coagulation. |
coagulase
[kō·ag′yəlās]
Etymology: L, coagulare, to curdle
an enzyme produced by bacteria, particularly Staphylococcus aureus, that promotes the formation of fibrin from fibrinogen to form thrombi.
coagulase
an antigenic substance of bacterial origin, produced chiefly by staphylococci, which may be causally related to thrombus formation.
coagulase test
enzymatic conversion of fibrinogen in rabbit plasma to fibrin is used as a means of identifying pathogenic species of staphylococci. The test may be carried out rapidly on a slide or in several hours or overnight in a tube. Most coagulase-positive staphyloccoci are pathogenic; coagulase-negative ones commonly are not.
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