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coagulase

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coagulase /co·ag·u·lase/ (-las) an antigenic substance of bacterial origin, produced by staphylococci, which may be causally related to thrombus formation.
co·ag·u·lase (k-gy-ls, -lz)
n.
An enzyme, such as rennin or thrombin, that induces coagulation.

coagulase
an antigenic substance of bacterial origin, produced chiefly by staphylococci, which may be causally related to thrombus formation.

coagulase test
enzymatic conversion of fibrinogen in rabbit plasma to fibrin is used as a means of identifying pathogenic species of staphylococci. The test may be carried out rapidly on a slide or in several hours or overnight in a tube. Most coagulase-positive staphyloccoci are pathogenic; coagulase-negative ones commonly are not.

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All frost cultures were positive for at least one pathogenic micro-organism: 78% coagulase negative Staphylococcus; 37% Bacillus spp: 18% Staphylococcus aureus; 11% alpha-haemolylic Streptococcus; 9% Pseudomonas ssp; 3% Stenotrophomonas maltophilia and 11% other Gram-negative organisms.
The authors found that coagulase negative S aureus was the most common organism cultured from both institutions, at both the drain and the agitator and at both times of day.
The increased use is explained by documented cases of coagulase negative staphylococcus and methicillinresistant staphylococcus aureus in the hospital.
 
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