coagulase


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Related to coagulase: staphylokinase, Leukocidins

coagulase

 [ko-ag´u-lās]
a bacterial enzyme that reacts with a cofactor found in blood plasma to catalyze the formation of fibrin from fibrinogen. It is produced by most of the virulent strains of staphylococci, and by Yersinia pestis.

coagulase

/co·ag·u·lase/ (-lās) an antigenic substance of bacterial origin, produced by staphylococci, which may be causally related to thrombus formation.

coagulase

(kō-ăg′yə-lās′, -lāz′)
n.
Any of various enzymes, such as rennin or thrombin, that induce coagulation.

coagulase

[kō·ag′yəlās]
Etymology: L, coagulare, to curdle
an enzyme produced by bacteria, particularly Staphylococcus aureus, that promotes the formation of fibrin from fibrinogen to form thrombi.

coagulase

An enzyme secreted by the micro-organism Staphylococcus aureus that causes clotting in blood plasma by converting prothrombin to thrombin. This ability probably contributes to the tendency of the organism to form abscesses.

coagulase

an antigenic substance of bacterial origin, produced chiefly by staphylococci, which may be causally related to thrombus formation.

coagulase test
enzymatic conversion of fibrinogen in rabbit plasma to fibrin is used as a means of identifying pathogenic species of staphylococci. The test may be carried out rapidly on a slide or in several hours or overnight in a tube. Most coagulase-positive staphyloccoci are pathogenic; coagulase-negative ones commonly are not.
References in periodicals archive ?
Coagulase gene typing of Staphylococcus aureus isolated from cows with mastitis in southeastern Brazil.
aureus based on the results of tube coagulase, mannitol fermentation and growth in 7.
Coagulase negative staphylococci was the main bacteria isolated in this study on both BEFORE (25.
Para os procedimentos de Coliformes a 45[degrees]C e Estafilococos coagulase positivo, foram pesados assepticamente 25 g de amostra, homogeneizados em 225 mL de Agua Peptonada esteril e, a partir da homogeneizacao, preparadas diluicoes seriadas em tubos estereis ate [10.
Coagulase testing compared with commercial kits for routinely identifying Staphylococcus aureus.
staphylococcus protein A (a super antigen), leukocidins, and coagulase itself.
aureus by culture and biochemical tests which included test for clumping factor, free coagulase and mannitol fermentation.
5 mL rabbit plasma (Becton Dickinson) to test for the production of coagulase.
Vancomycin is the critically important antibiotic to treat neonatal Late Onset Sepsis (LOS) due to Gram positive bacteria in neonates, including Coagulase Negative Staphylococci (CoNS) and Staphylococcus aureus.
The most common blood culture contaminant is usually Coagulase Negative Staph (CoNS).
Table 1: Bacteria obtained from culturing Samples of canine corneal ulcers Percent Number of dogs Bacteria 28 6 Staphylococcus coagulase + 23 5 Staphylococcus coagulase - 4 1 Pseudomonas 4 1 Streptococcus 4 1 Fungus 37 8 Negative culture 100 22 Total Table 2: Performed Treatment on corneal ulcers in dogs Treatment Number of dogs Percent Ciprofloxacin and amikacin drops 12 54 Conjunctival flap with topical drops 6 28 Eye evisceration in time references 4 18 Total 22 100
The Bacti-Staph[R] Latex 150 Test Kit was used to detect coagulase in staphylococci isolates.