clotting factor


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Related to clotting factor: hemophilia

clot·ting fac·tor

any of the various plasma components involved in the clotting process.
Synonym(s): coagulation factor

clotting factor

Coagulation factor. See Factor.

clot·ting fac·tor

(klot'ing fak'tŏr)
Any of the various plasma components involved in the clotting process.

Clotting factor

Also known as coagulation factors. Proteins in the plasma which serve to activate various parts of the blood clotting process by being transformed from inactive to active form.
Mentioned in: Coagulation Disorders

clot·ting fac·tor

(klot'ing fak'tŏr)
Any plasma components involved in clotting.
References in periodicals archive ?
Blood clotting, which involves the interplay of cellular elements called platelets and a number of clotting factors that bear common and Roman numeral names, plays an important role in maintaining the integrity of blood vessels.
The addition of small amounts of the patient's plasma to normal plasma (containing clotting factor activities of about 100 IU/dL, thereby balancing potential clotting factor deficiencies) produced severe and nonlinear aPTT prolongation (see Fig.
7) These clotting factors and fibrinogen are critical for normal hemostasis.
Some civilian surgical teams have also recommended increasing the focus on early and aggressive replacement of clotting factors in the resuscitation process following massive hemorrhage.
In a series of eight consecutive hemophiliac patients with chronic hepatitis C virus (HCV) infection treated at one center with a combination of ribavirin and interferon alfa-2b, five patients had moderate or severe hemophilia that required significantly less use of clotting factors on average during each month of treatment than in the 6 months prior to combination therapy (1,605 U/mo vs.
An adult with severe hemophilia typically will experience eight to 10 bleeds per month and self-administer 1,500 to 4,000 units of clotting factor per infusion.
Patients with factor IX levels that are 5% or more of normal typically require infusion of clotting factor only after an accident or for surgery.
The addition of a human cell is expected to enable the clones, when they grow up and reproduce, to provide milk containing a human clotting factor that can be used to heal people with haemophilia, Wong said.
Cell Genesys is pursuing gene therapies for hemophilia A and hemophilia B -- genetic deficiencies in factor VIII and factor IX clotting factor genes, respectively.
This means their blood lacks an essential clotting factor.
The incidence of von Willebrand disease - which is similar to hemophilia but different in that the deficient clotting factor does not always remain at the same level - is not known.
Recent evolution of clotting factor concentrates for hemophilia A and B.