Clostridial myonecrosis | definition of clostridial myonecrosis by Medical dictionary
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gangrene occurring in a wound infected with various anaerobic spore-forming bacteria, especially Clostridium perfringens and C. novyi, which cause rapidly advancing crepitation of the surrounding tissues, due to gas liberated by bacterial fermentation, and constitutional toxic and septic symptoms including cytotoxic damage to kidney, liver, and other organs.
clostridial myonecrosis Gas gangrene, necrotizing subcutaneous infection Emergency medicine A rapidly progressive, life-threatening form of gangrene that is a rare complication of 'dirty' traumatic wounds, which are infected with Clostridium spp Etiology War wounds, bee stings, venipuncture; CM is due to production of toxins, especially alpha toxin, leading to tissue necrosis, shock Management Surgical decompression, excision of necrotic tissue, penicillin, hyperbaric oxygen. See Hyperbaric oxygen therapy, Necrotizing fasciitis.
References in periodicals archive
Carcinoma of the large intestine and nontraumatic, metastatic, clostridial myonecrosis