Clostridial myonecrosis | definition of clostridial myonecrosis by Medical dictionary
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gangrene occurring in a wound infected with various anaerobic spore-forming bacteria, especially Clostridium perfringens and C. novyi, which cause rapidly advancing crepitation of the surrounding tissues, due to gas liberated by bacterial fermentation, and constitutional toxic and septic symptoms including cytotoxic damage to kidney, liver, and other organs.
clostridial myonecrosis Gas gangrene, necrotizing subcutaneous infection Emergency medicine A rapidly progressive, life-threatening form of gangrene that is a rare complication of 'dirty' traumatic wounds, which are infected with Clostridium spp Etiology War wounds, bee stings, venipuncture; CM is due to production of toxins, especially alpha toxin, leading to tissue necrosis, shock Management Surgical decompression, excision of necrotic tissue, penicillin, hyperbaric oxygen. See Hyperbaric oxygen therapy, Necrotizing fasciitis.
References in periodicals archive
These animals died between 2000 and 2015 with clinical and pathological findings consistent with clostridial myonecrosis.
2016), presence of changes consistent with myonecrosis, in the absence of marked autolytic alterations, and associated with the bacteria in situ indicated that the disease occurred and allowed the definitive diagnosis of clostridial myonecrosis.
Excruciating pain is a significant clinical symptom of clostridial myonecrosis
Novel real-time PCR assay for simultaneous detection and differentiation of Clostridium chauvoei and Clostridium septicum in clostridial myonecrosis