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clonogenic |
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clonogenic /clo·no·gen·ic/ (klo″no-jen´ik) giving rise to a clone of cells.
clonogenic giving rise to a clone of cells. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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When DNA damage is irreparable, checkpoints also inactivate clonogenic survival by permanent cell cycle arrest or apoptosis. GX15-070 potently inhibited the clonogenic ability of AML blasts at sub-micromolar doses and, in 6/7 primary AML samples, induced apoptosis in CD34+ progenitor cells. A population of cells representing less than 5 percent of the cells in the bulk population of multiple myeloma cells was found to be CD138 negative, and possessed in vitro clonogenic potential. |
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