28) The dose at which caraway exhibited 50% of its maximal effect in delaying the onset time to myoclonic and clonic seizures
(ED50) was determined by GraphPad Prism, version 5.
One can notice the first case particularity, the tonic clonic seizure
complications secondary to cerebral involvement.
however, induced a dose-dependent decrease in the incidence of both minimal clonic seizures
On the other hand, a comparison of the muscle relaxant and anticonvulsant effects between Diazepam and Guaifenesin in the current study showed that although Guaifenesin at doses of 300 and 400 mg/ kg had more profound effects on muscle relaxation than Diazepam, the effects of Guaifenesin at similar doses in preventing myoclonic and clonic seizures
were less marked than those of Diazepam.
5 %) had multiple seizures in the form of generalized tonic clonic seizures
and myoclonic seizures, 3 cases (37.
were found to be the most common type of seizures 24(40%) in the present study, followed by subtle 19 (31.
If a generalized tonic clonic seizure
lasts longer than five to ten minutes, medical intervention is needed, either by administering rectal diazepam (see "Advanced" first aid) or via emergency medical services.
Sometimes these become generalized tonic clonic seizures
Patients with drug refractory epilepsy, include atonic, clonic, myoclonic, absence, tonic clonic seizures
, after two years treatment with at least two anticonvulsive drugs (15,37,38,49,50,51);
are repetitive, rhythmic jerks that involve both sides of the body at the same time.
India) by her mother to "help her to go to sleep" with the recommendation of the family members, had generalized tonic clonic seizures
one hour after ingestion (the first one lasted for 3-4 minutes and stopped spontaneously and the second one could be stopped only after 10 minutes with eight mg diazepam) and was referred to our hospital after the case was reported to the legal authorities.
There are no credible evidence of anticonvulsant effect of this plant in bibliographic resources and databases, so methanolic extracts of papaver somniferum on generalized tonic seizures and clonic seizures
induced by picrotoxin in mice has been studied.