clofibrate /clo·fi·brate/ (-fi´brāt) an antihyperlipidemic used to reduce serum lipids.
Clofibrate (Altromed-S)
clofibrate
clofibrate (klōfī´brāt),
clo·fi·brate (kl -f  br t, -f brt)n. A synthetic drug formerly prescribed to reduce abnormally elevated levels of plasma cholesterol and triglyceride. |
Clofibrate (Altromed-S)
Medication used to lower levels of blood cholesterol and triglycerides.
Mentioned in: Thyroid Function Tests
clofibrate
[klō′fəbrāt]
an antihyperlipidemic.
indications It is prescribed in the treatment of high blood levels of triglycerides occurring alone or in combination with high cholesterol levels.
contraindications Liver or kidney dysfunction, pregnancy, lactation, biliary cirrhosis, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse reactions are nausea, diarrhea, weight gain, and a syndrome resembling influenza. This drug interacts with many other drugs and should not be used together with the HMG-CoA reductase inhibitors (statins) used to lower plasma cholesterol levels because this combination has an increased risk for myositis and rhabdomyolysis.
clofibrate (klōfī´brāt),
n brand names: Abitrate, Atromid-S, Claripex, Novofibrate;
drug class: antihyperlipidemic;
action: inhibits biosyntheis of VLDA and LDL, which are responsible for triglyceride development; increases excretion of neutral steroids;
use: hyperlipidemia types III, IV, V.
drug class: antihyperlipidemic;
action: inhibits biosyntheis of VLDA and LDL, which are responsible for triglyceride development; increases excretion of neutral steroids;
use: hyperlipidemia types III, IV, V.
clofibrate
an antihyperlipidemic drug.
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