clofibrate

clofibrate /clo·fi·brate/ (-fi´brāt) an antihyperlipidemic used to reduce serum lipids.

---

clo·fi·brate (kl-fbrt, -fbrt)

n.

A synthetic drug formerly prescribed to reduce abnormally elevated levels of plasma cholesterol and triglyceride.

---

Clofibrate (Altromed-S)

Medication used to lower levels of blood cholesterol and triglycerides.

Mentioned in: Thyroid Function Tests

---

clofibrate

[klō′fəbrāt]

an antihyperlipidemic.

indications It is prescribed in the treatment of high blood levels of triglycerides occurring alone or in combination with high cholesterol levels.

contraindications Liver or kidney dysfunction, pregnancy, lactation, biliary cirrhosis, or known hypersensitivity to this drug prohibits its use.

adverse effects Among the more serious adverse reactions are nausea, diarrhea, weight gain, and a syndrome resembling influenza. This drug interacts with many other drugs and should not be used together with the HMG-CoA reductase inhibitors (statins) used to lower plasma cholesterol levels because this combination has an increased risk for myositis and rhabdomyolysis.

---

clofibrate [klo-fi´brāt]

an agent used to reduce elevated serum lipids in treatment of hyperlipoproteinemia, administered orally.

---

clofibrate (klōfī´brāt),

n brand names: Abitrate, Atromid-S, Claripex, Novofibrate;
drug class: antihyperlipidemic;
action: inhibits biosyntheis of VLDA and LDL, which are responsible for triglyceride development; increases excretion of neutral steroids;
use: hyperlipidemia types III, IV, V.

---

clofibrate

an antihyperlipidemic drug.