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(klok) a device for measuring time.
biological clock  the physiologic mechanism which governs the rhythmic occurrence of certain biochemical, physiologic, and behavioral phenomena in living organisms.


1. An instrument other than a watch for measuring or indicating time, especially a mechanical or electronic device having a numbered dial and moving hands or a digital display.
2. A biological clock.
v. clocked, clocking, clocks
To register or record with a mechanical device: clocked the winds at 60 miles per hour.

clock′er n.


A gene on chromosome 4q12 that encodes a ubiquitously expressed human homolog of the mouse clock gene, which forms a heterodimer with ARNTL and activates E-box element transcription of several circadian clock proteins (e.g., PER1 and PER2). CLOCK is highly expressed in the suprachiasmatic nucleus.

Molecular pathology
CLOCK-ARNTL double mutations in the PAS domains result in syngernistic desensitisation to high levels of CRY on repression of CLOCK-ARNTL transcriptional activity of PER1, disrupting circadian rhythmicity.


A device for measuring time.

biological clock

1. An internal system in organisms that influences behavior in a rhythmic manner. Functions such as growth, feeding, secretion of hormones, the rate of drug action, the wake-sleep cycle, the menstrual cycle, and reproduction coincide with certain external events such as day and night, the tides, and the seasons. Biological clocks appear to be set by environmental conditions in some animals, but if these animals are isolated from their environment they continue to function according to the usual rhythm. A gradual change in environment does produce a gradual change in the timing of the biological clock. See: circadian; maladaptation to night work; zeitgeber
2. A colloquial term for the decrease in fertility that accompanies aging, particularly as women approach the age of 35.

Patient discussion about clock

Q. How do you wake up in the morning if your narcolepsy is so severe you can't hear the alarm clock, phone ring? biggest problem is sleep paralysis, can't wake up. Late for work, everything, life is suffering because of severity. Have tried ritalin, natural supplements, hypnosis therapy, Provigal, antidepressants, nothing seems to work. Employer thinks it's an excuse, friends are irritated, I'm at my wits end. Life is spent sleeping more than awake.

A. Narcolepsy cannot yet be cured. But EDS and cataplexy, the most disabling symptoms of the disorder, can be controlled in most patients with drug treatment. Often the treatment regimen is modified as symptoms change. For decades, doctors have used central nervous system stimulants-amphetamines such as methylphenidate, dextroamphetamine, methamphetamine, and pemoline-to alleviate EDS and reduce the incidence of sleep attacks. For most patients these medications are generally quite effective at reducing daytime drowsiness and improving levels of alertness. However, they are associated with a wide array of undesirable side effects so their use must be carefully monitored. Common side effects include irritability and nervousness, shakiness, disturbances in heart rhythm, stomach upset, nighttime sleep disruption, and anorexia. For full article: Hope this helps.

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Simon Rowe said: "In a difficult economic climate, it is pleasing that we have played a part in a deal that has not only saved a substantial number of jobs but should see the secured creditor repaid in full and a return to Clockwork Services' other creditors.
A Clockwork Orange was turned into a film in 1971 by director Stanley Kubrick and director Phil Swinburne says the People's Theatre production had borrowed many elements of the cult film.
THERE was a time when the merest mention of A Clockwork Orange would send the Mary Whitehouses in our midst into a frenzy of gasps and clenched hands.
Top Ten: 1 Travis Bickle (Robert De Niro - Taxi Driver, 1976) 2 Leon (Jean Reno - Leon, 1994) 3 D-Fens (Michael Douglas - Falling Down, 1993) 4 Harry Callahan (Clint Eastwood - Dirty Harry, 1971) 5 Alex DeLarge (Malcolm McDowell - A Clockwork Orange, 1971) 6 Mad Max (Mel Gibson - Mad Max, 1979) 7 Dr Hannibal Lecter (Anthony Hopkins - The Silence of the Lambs, 1991) 8 Jack Carter (Michael Caine - Get Carter, 1971) 9 Snake Plissken (Kurt Russell - Escape from New York, 1981) 10 John Rambo (Sylvester Stallone - First Blood, 1982)
This philosophy was known as the belief in a clockwork universe.
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THE poster for Stanley Kubrick's cult film A Clockwork Orange is the best ever, according to movie fans.
Second was Stanley Kubrick's notorious A Clockwork Orange.