clinical trials


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Related to clinical trials: Clinical research

clinical trials

organized studies to provide large bodies of clinical data for statistically valid evaluation of treatment to determine safety and efficacy.

Clinical trials

Highly regulated and carefully controlled patient studies, where either new drugs to treat cancer or novel methods of treatment are investigated.
Mentioned in: Head and Neck Cancer

clinical

1. pertaining to a clinic or to the bedside and therefore carried out on the living animal.
2. pertaining to or founded on actual observation and treatment of patients, as distinguished from theoretical or experimental.
3. productive of clinical signs; thus clinical disease as distinct from subclinical.

clinical data storage
storage of clinical data about patients; may be paper or computerized.
clinical decision analysis
the application of clinical, epidemiological and other data to influence outome probability and alternative decisions in such areas as surgery and pharmaceutical treatment.
clinical epidemiologist
an epidemiologist who sees patients and herds in a clinical capacity but with an epidemiological viewpoint. An investigator of clinical problems affecting populations.
clinical epidemiology
the application by a veterinarian who provides direct patient care of epidemiological methods to the study of diagnosis and therapeutics in order to promote efficiency in clinical care.
clinical examination
an examination of a patient including taking the history, physical examination by palpation, auscultation and percussion, clinicopathological examination and examination of the environment.
clinical judgment
exerted while the patient is still alive; the critical decisions made on the basis of scientific observations but with the added skill provided by long experience of similar cases. To this must be added an innate ability to make balanced judgments based not only on the state of the animal and its predictable future but also on some consideration for the patient's overall well-being and the client's financial status and degree of psychological, or in some cases actual, dependence on the patient.
clinical nomenclature
a catalog of the names given to diseases and problems of animals; usually alphabetical, may be numerical. Should contain keywords (including key diagnoses and key signs) and synonyms with each list related to the other. Because of the need to sort banks of clinical data into categories it is essential that recording be accurate and that the catalog be limited—a policy of limited vocabulary.
clinical pathologist
a veterinarian skilled in clinical pathology.
clinical pathology
the examination of diseased tissues, fluids or other materials from a living patient, using all of the techniques available including chemistry, hematology, enzymology, cytology, microbiology, parasitology, protozoology, immunology and histopathology.
clinical pharmacology
the study of the actions and metabolism of drugs in living animals.
clinical policies
professional rules of thumb which are used to decide on the management of a case when there are no research results on which to base decisions. They are policies originated by the senior members of the profession, especially those in academic posts.
clinical propedeutics
preliminary training in the clinical sciences; the introduction to veterinary medicine, surgery and animal reproduction.
clinical qualifiers
adjectives used to qualify diagnoses using terms from within a group of standard variables, e.g. chronic or acute, ovine or bovine, benign or malignant, clinical or latent.
clinical record
the record, made at the time, of clinical examinations, treatments and advice given, complete with dates, names of individuals concerned and drugs or tests used. The record is desirable for the purpose of evaluating the patient's progress, and essential from the legal point of view if arguments should arise about competence or justness of charges made.
clinical signs
the abnormalities of structure or function observed in the patient by the veterinarian or the client. These are customarily graded according to severity, e.g. severe, moderate, mild, and according to speed of onset and progress, e.g. peracute, acute, subacute, chronic, intermittent.
clinical trials
a planned experiment, conducted in the field, designed to test the efficacy of a treatment in herds of animals by comparing the outcome under the test treatment with that observed in a comparable group of animal herds receiving a control treatment.
clinical vocabulary
a catalog of terms approved for use in the description of clinical signs and problems, and for the definition of diagnoses and diseases.
References in periodicals archive ?
All of these resources are devoted solely to conducting clinical trials.
For clinical trials at this stage, statistically relevant numbers of participants are essential, so they are often conducted at a number of different sites.
Top Companies Participating in Tourette Syndrome Therapeutics Clinical Trials
While many health plans may have been interested in limiting coverage of ABMT for breast cancer to clinical trials, for most plans there was no contractual basis to do so, and widespread insurance coverage tends to dampen enthusiasm for participation in clinical trials.
Additionally, there is a concern regarding the quality of clinical trials.
Amyotrophic Lateral Sclerosis Global Clinical Trials Review, Q1, 2011
Clinical trials and the clinical research physician
Salata, MD, Chief of Division of Infectious Diseases and HIV Medicine at University Hospitals Case Medical Center and Co-Principal Investigator of the Case Medical Center Clinical Trials Unit.
XenoPort plans to conduct an additional Phase 1 escalating repeat-dose clinical trial of the potential once-a-day formulation in healthy subjects prior to initiating a Phase 2 clinical trial in patients with GERD in the second half of this year.
However, at the doses used in SILENOR[TM] in controlled clinical trials completed by Somaxon to date, SILENOR[TM] has been well tolerated.
Nasdaq: CRTX) today announced that the National Institutes of Health (NIH) will sponsor and fund a clinical trial to evaluate whether using ZYFLO[R] (zileuton tablets) to treat patients admitted to the hospital with acute exacerbations of chronic obstructive pulmonary disease (COPD) will shorten their hospital stay.
Nasdaq: CYCC, NASDAQ: CYCCP) announced today that it has submitted an Investigational New Drug (IND) application to the Food and Drug Administration (FDA) to begin clinical trials of CYC116, the company's orally available inhibitor of Aurora kinases A & B and VEGFR2.

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