In addition, the assay must have a high clinical specificity
to rule out those patients who do not have DVT or PE.
1) and a previous study (3) has been shown to have a very high clinical specificity
Clinical sensitivity, clinical specificity
, positive predictive value, and negative predictive value were calculated with the conventional contingency tables, and 95% confidence intervals (95% CI) were computed using the exact binomial method.
As expected, the absolute clinical specificity
for CIN2+/CIN3+ varied greatly across studies due to the heterogeneous nature of the referral populations (Table 1).
Constructivist therapy often gets labeled as too theoretical and lacking in clinical specificity
Analytical and clinical specificity
can also be impacted by aspects such as sample collection, storage and stability.
There also is a lack of EEG and clinical specificity
to associate epileptic encephalography with autistic regression, because most children with autistic regression on overnight EEG testing do not have epileptiform activity and there is no clinical difference between children with autistic regression and those with nonregressive ASD.
This is largely due to significant levels of unmet medical need and the clinical specificity
of many CNS drugs.
Numerous studies have demonstrated that the mRNA-based hrHPV assay has higher clinical specificity
for detection of cervical cancer lesions than DNA-based hrHPV assays (8,10) (Figure 1).
Although EIA demonstrated good clinical specificity
(ie, few positive results among patients with low likelihood of disease), it was not especially useful for detecting patients with high disease probability (suggesting low clinical sensitivity).
Given that lipase remains increased for longer periods of time and has higher clinical specificity
, as Dr.
The cutoff concentration for the Bayer ADVIA Centaur assay was set at 100 ng/L to maximize clinical specificity
(>97%) and to be greater than the upper confidence limit of the 95th percentile of the non-HF reference population.