clinical significance

clinical significance

A change in a patient’s/subject's clinical status that is regarded as important, whether or not it is due to an intervention in the context of a clinical trial. The phrase clinical significance should not be used unless it is operationally defined.

clinical significance

Medtalk A conclusion that an intervention has an effect of practical meaning to Pts and health care providers; even though an intervention is found to have a statistically significant effect, this effect might not be clinically significant
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The thirteen selections that make up the main body of the text are devoted to the history of staphylococcus aureus, the clinical significance of staphylococcus in humans, the clinical significance of the bacteria in animals, and a wide variety of other related subjects.
Rainer Krahenmann this observation is of major clinical significance because current available drugs for the treatment of depression and anxiety disorders are not effective in all patients and are often associated with unwanted side effects.
In this column, I will discuss the meaning of the tests of significance as well as how statistical significance relates to clinical significance.
The annotated content may aid physicians' understanding, through the database, of the clinical significance of test results indicating the presence of one or more gene mutations.
There is a risk of focusing too heavily on statistical significance without full appreciation of the potentially broader clinical significance of results.
The trend shows no evidence for abatement and may indicate increasing epidemiologic and clinical significance," the study's authors wrote.
Cells with distinct phenotypes including stem-cell-like properties have been proposed to exist in normal human mammary epithelium and breast carcinomas, but their detailed molecular characteristics and clinical significance are unclear.
Hence it is misnomer that if the results are statistically significant then the therapy is of clinical significance.
She also addresses evaluating study credibility, clinical significance, and clinical applicability, with example articles and commentary in both the research and evidence chapters.
Moreover, the panel acknowledged that the clinical significance of HER2 GH regarding the potential benefit from trastuzumab therapy is unclear.
All interactions are graded according to three guides presented at the front of the book: the interaction probability guide; the type and clinical significance guide; and the strength and character of source evidence guide.
While you can question the clinical significance of a 26-minute operating room difference .

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