Despite the significant clinical burden
, little progress has been made in terms of therapeutic development.
Does the Increasing Clinical Burden
Permit us to Leave Physicians Untrained for Their Non-clinical Roles?
Although the primary abnormality in NAFLD affects liver structure and function and may result in cirrhosis, liver failure, and hepatocellular carcinoma, the clinical burden
of NAFLD is not confined to liver-related morbidity and mortality," wrote Dong Hyun Sinn, MD, PhD, of Samsung Medical Center in Seoul, South Korea, and coauthors.
We must know the actual clinical burden
to plan intervention strategies.
Identifying modifiable risk factors for cataracts may help establish preventive measures and reduce the financial, as well as clinical burden
, caused by the disease.
Identifying modifiable risk factors for cataracts may help establish preventive measures and reduce the financial as well as clinical burden
caused by the disease," Ye said.
The pathogenesis of erosive hand OA remains poorly understood, despite its high clinical burden
, the researchers noted.
Global clinical burden
of malaria (how many people become ill because of malaria and where they live) is required to direct resources where it will have most impact.
Globally, the annual death rate from RSV is estimated at more than 160,000 and the clinical burden
of RSV infection is comparable to that of influenza.
Cellulitis is responsible for 184,000 hospital admissions and 1,300 deaths in the United States each year, so the clinical burden
from these conditions is considerable, Dr.
Given its economic and clinical burden
, heart failure is one of the most challenging problems currently plaguing the global healthcare system," said Pat Mackin, president of the Cardiac Rhythm Disease Management business and senior vice president at Medtronic.
New data presented today demonstrate the severe clinical burden
of paroxysmal nocturnal hemoglobinuria (PNH) and the clinical benefits of Soliris([R]) (eculizumab) in 44 patients with no history of prior blood transfusions.