clinging DCIS

clinging DCIS

A type of ductal carcinoma in situ (DCIS) which was underdiagnosed in the past; at the malignant end of a spectrum of ductal changes that begin with benign blunt duct adenosis/columnar cell alteration. It is probably a variant of low-grade micropapillary DCIS.
References in periodicals archive ?
A European classification system of DCIS recognized clinging pattern as another variant of DCIS (4) and by using Azzopardi's criteria recommended a separation between well-differentiated (monomorphic variant with low-grade atypia) and poorly differentiated (pleomorphic variant with high-grade atypia) clinging DCIS.
Moreover, many pathologists were uncertain about the true neoplastic nature of atypical epithelial cells lining the ducts, particularly in the well-differentiated or monomorphic variant (with mild nuclear atypia) of clinging DCIS (F.
After publication of the first molecular-genetic study6 on the issue of clinging DCIS in 2000, it became clear that both variants of this type of flat lesion represent neoplastic alterations of the breast and share many similarities with other more conventional patterns (types) of DCIS.