clemastine


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clemastine

 [klem´as-tēn]
an antihistamine with sedative and anticholinergic effects; used as the fumarate salt in the treatment of nasal, eye, and skin manifestations of allergic reactions, including allergic rhinitis, conjunctivitis, and itching, and also as an ingredient in cough and cold preparations, administered orally.

clemastine

/clem·as·tine/ (klem´as-tēn) an antihistamine with anticholinergic and sedative effects, used as the fumarate salt.

clemastine

[klemas′tēn]
an antihistamine.
indications It is prescribed in the treatment of symptoms of allergic rhinitis, pruritus, or conjunctivitis.
contraindications Use by lactating mothers or those undergoing monamine oxidase inhibitor therapy or having known sensitivity to this drug or other antihistamines is contraindicated. It is also contraindicated with narrow-angle glaucoma, asthma, symptomatic prostatic hypertrophy, and bladder-neck destruction.
adverse effects Among the most serious adverse reactions are hypersensitivity, skin rash, and tachycardia. Transient drowsiness commonly occurs.

clemastine

A sedating antihistamine and anticholinergic used for managing allergic rhinitis and hay fever.

Adverse effects
CNS depression or stimulation; the latter is more common in children and may be accompanied by excitement, hallucinations, ataxia, incoordination, spasms, athetosis, hyperthermia, cyanosis, hyperreflexia and cardiorespiratory arrest.

clemastine

An ANTIHISTAMINE drug used to treat hay fever and other allergic conditions. A brand name is Tavegil.
References in periodicals archive ?
More than 2,800 first-trimester exposures to clemastine have been reported.
Take a sustained-release first-generation antihistamine like brompheniramine (Lodrane 24) or clemastine (Tavist Allergy 12-Hour Relief Tablets), In recent clinical trials, their effectiveness against sneezing, runny nose, and possibly cough has been impressive.
Traditional first-generation antihistamines, such as chlorpheniramine, diphenhydramine and clemastine, are effective at reducing the symptoms of SAR.
FDA classification of selected antihistamines Category Drug B Azatadine Cetirizine Chlorpheniramine Clemastine Dimenhydrinate Diphenhydramine Loratadine C Azelastine Brompheniramine Fexofenadine Hydroxyzine Promethazine Table 4.
Specifically, NovaDel's patent is directed to buccal aerosol spray compositions for delivering a number of active compounds including, clemastine (Tavist ), nicotine, testosterone, estradiol, progesterone, fluoxetine (Prozac) and piroxicam (Feldene).
No interferences were observed from endogenous compounds and various drugs that are potentially coadministered with MMF, such as acetaminophen, amikacin, amoxicillin, amphotericin B, caffeine, carbamazepine, cefazolin, chloramphenicol, cimetidine, clemastine, clonazepam, cyclosporin A, diazepam, digoxin, dopamine, gentamicin, lidocaine, netilmicin, phenobarbital, phenytoin, prednisolone, prednisone, primidone, rapamycin, salicylate, tacrolimus, theophylline, tobramycin, and vancomycin.
Take a sustained-release, first-generation antihistamine (the kind that can make you drowsy) like diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), bromphenifamine (Dimetapp), or clemastine (Contac, Tavist).
Antihistamines such as mizolastine and clemastine may provide some relief from itching(2).
In one case with clemastine (Tavist), the infant also had neck stiffness and high-pitched crying.
Acetaminophen Cyclosporine A Phenobarbital Amikacin Desipramine Phenytoin Amitriptyline Diazepam Prednisolone Amoxicillin Digoxin Prednisone Amphotericin B Disopyramide Primidone Caffeine Dopamine Quinidine Carbamazepine Ethosuximide Rapamycin Cefazolin Gentamicin Salicylate Chloramphenicol Imipramine Tacrolimus Cimetidine Lamotrigine Theophylline Clemastine Lidocaine Tobramicin Clonazepam Netilmicin Vancomycin Table 2.
Dugger III, President of the Company stated that in his opinion, the pilot studies already carried out by the Company on nicotine, clemastine, estradiol, progesterone and nitroglycerin have verified the ability of the Company's lingual spray delivery system to delivery therapeutic levels of medication to the body rapidly and at lower dosages.
The company's lingual spray formulation of clemastine fumarate, the active ingredient in Tavist(R)(a), is being developed for the rapid treatment of hay fever symptoms.