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leukoencephalopathy with vanishing white matter

A leukodystrophy of childhood onset (OMIM:603896) characterised by progressive cerebellar ataxia, spasticity, variable optic atrophy and relatively preserved mental abilities. Leukodystrophy with vanishing white matter is usually slowly progressive, but may undergo rapid deterioration after fever or minor head trauma. Clinical variants include a severe, early-onset form seen among the Cree and Chippewayan populations of Quebec and Manitoba (Cree leukoencephalopathy), and a milder form affecting females who survive to adolescence and exhibit ovarian dysfunction (ovarioleukodystrophy).

Molecular pathology
Defects in EIF2B1, which encodes a subunit of eukaryotic translation initiation factor 2B (EIF2B), an essential regulator of protein synthesis, are a cause of leukodystrophy with vanishing white matter.

Cle

total elimination clearance.

Patient discussion about Cle

Q. Cn barret esophagous be cured? I was diagnosed with barretts esophagus several years ago, and so far keeps on the routine follow up. I met some other guy with same condition and he told after his doctor prescribed him with some anti-reflux meds, in the last endoscopy they found normal esophagus, and that he thinks he's now cured. Is that possible?

A. Anti-reflux treatment may lower the risk of cancer a little, but it won't cure it, so there's still a need for refular follow-up.

More discussions about Cle
References in periodicals archive ?
In order to secure the most information-rich cases and a wide range of viewpoints, one student was selected at each site to fill the following descriptions: 1) a treble clef choir member, 2) a female auditioned mixed choir member, 3) a female non-auditioned mixed choir member, 4) a male mixed choir member, and 5) a former women's choir member who is now singing in a mixed choir.
Nordoff Robbins (Scotland) executive director Mary Brown said: "It is hoped that the increased profile the Tartan Clef awards bring will enable even more children and adults to receive music therapy.
This is a relatively minor problem because, to my knowledge, it is purely a matter of editorial style, and the clef never changes within a piece.
Les Clefs d'Or has over 40-member countries with more than 4,000 members.
Beginning in 1700, other prominent features were also punched, including the flat sign and expressive markings, although the bass clef is still engraved by hand.
Because the whole point of a roman a clef is to play a guessing game: Which character is based on which real person?
The Eurythmics won the coveted Silver Clef award following their succesful comeback with a new album, Peace.
Dans leur deposition au niveau de la surete de daira de Bou-Ismail, les deux ressortissants chinois ont declare que les voleurs leur ont subtilise la somme de 20 millions de centimes, des dossiers administratifs et une clef USB contenant des documents sensibles qui concernent la societe oE ils travaillent.
The Mullingar teenager and the lads are currently on the road in the US with their Take Me Home tour and could not pick up the prize at the Nordoff Robbins O2 Silver Clef Awards.
In "Change My Heart, Oh God" sixth intervals and quarter-note triplets in the treble clef provide unique fillers between the right-hand melody phrases played in the bass clef.
28, 2012 /PRNewswire/ -- Produced by Sir Clef featuring OutKast's Andre 3000, "Sorry" is one of the most talked about collabs launching from T.