Glandular cells and clear cells
make up the remaining cell types.
Pathologic differential diagnosis of clear cell
squamous cell carcinoma in situ: conditions with intraepidermal Pagetoid cells Clear cell
papulosis Clear cell
squamous cell carcinoma in situ Clear cells
of Toker (of the nipple epidermis) Extramammary Paget disease Cutaneous T-cell lymphoma Eccrine porocarcinoma Histiocytosis X (Langerhans cell histiocytosis) Langerhans cell microabscess (in cutaneous delayed hypersensitivity reactions) Malignant melanoma in situ (superficial spreading) Merkel cell carcinoma (with pagetoid intraepidermal spread) Metastasis (epidermotropic) Pagetoid dyskeratosis Paget disease (extramammary and mammary) Sebaceous carcinoma Spitz nevus (pagetoid) Table 2.
Eosinophilic lesions included lesions that were eosinophilic but could also have clear cells
, spindle cells, or hyaline cells.
Although frequently encountered, renal tumors with clear cells
, oncocytic cytoplasm, and papillary architecture can be diagnostically challenging (16); useful immunohistochemical panels to distinguish among the differential diagnoses are discussed here.
Punch biopsy HPE shows sheets and islands of large clear cells
separated by a delicate fibrous connective tissue stroma.
Although it has got a large tumour size; the lack of moderate to severe cytologic atypia and tumour cell necrosis, elevated mitotic rate, predominace of clear cells
with circumscribed margins pointed to benign behaviour.
EMC must be distinguished from primary salivary gland neoplasms that contain clear cells
9) Although clear cell
carcinoma of the pancreas may resemble metastatic clear cell
renal cell carcinoma by virtue of tubular/glandular structures lined by clear cells
with distinct cell borders and varying degrees of nuclear atypia, recognizable areas of conventional pancreatic ductal adenocarcinoma are usually present at least focally, thereby affording distinction between the 2 entities.
Microscopically, the tumour showed a solid pattern consists of sheets of clear cells
separated by delicate fibro vascularstroma.
3 Mostly, RCC with cutaneous metastases are clear cell
type, so microscopic differential diagnosis are xanthoma, xanthelasma, sebaceous tumours, balloon cell nevus, clear cell
hydradenoma and other skin lesions characterized by the presence of clear cells
The histopathologic picture of mucoepidermoid carcinoma includes varying proportions of cystic and solid epithelial elements made up of different proportions of mucous, epidermoid, intermediate, and clear cells
The dermis showed a well circumscribed cystic lesion arranged in lobules, comprising of clear cells
and basophilic cells.