clear cell

clear cell

1. a cell in which the cytoplasm appears empty with the light microscope, as occurs in certain secretory cells of eccrine sweat glands and in the parathyroid glands when the glycogen is unstained;
2. any cell, particularly a neoplastic one, containing abundant glycogen or other material that is not stained by hematoxylin or eosin, so that the cell cytoplasm is very pale in routinely stained sections.

clear cell

(klîr)
n.
A cell, especially a neoplastic one, containing abundant glycogen or other material that is not stained by hematoxylin or eosin, so that the cytoplasm appears clear histologically.

clear cell

Etymology: L, clarus + cella, storeroom
1 a type of cell found in the parathyroid gland that does not take on a color with the ordinary tissue stains used for microscopic examination.
2 the principal cell of most renal cell carcinomas and occasionally of ovarian and parathyroid tumors.
3 a specific type of epidermal cell, probably of neural origin, that has a dark-staining nucleus but clear cytoplasm with hematoxylin and eosin stain.
A finely vacuolated, cholesterol-filled cell with central dark nuclei, which is arranged in clusters and located in the midzone or zona fasciculata of the adrenal cortex. Clear cells are the major reservoir for glucocorticoid and sex hormone production when the adrenal gland is stressed

clear cell

(klēr sel)
1. A cell in which the cytoplasm appears empty with the light microscope, as occurs in certain secretory cells of eccrine sweat glands and in the parathyroid glands when the glycogen is unstained;
2. Any cell, particularly a neoplastic one, containing abundant glycogen or other material that is not stained by hematoxylin or eosin, so that the cell cytoplasm is very pale in routinely stained sections.
References in periodicals archive ?
Nodular hidradenoma, also known as clear cell hidradenoma or acrospiroma is a benign rare skin tumour arising from the eccrine type of sweat glands.
The FDA expanded indication was based on results from the S-TRAC trial, a multicenter, international, randomized, double-blind, placebo-controlled Phase 3 trial of SUTENT versus placebo in 615 patients with clear cell histology and high risk of recurrence following nephrectomy.
Liam Debbage, 31, was diagnosed with clear cell sarcoma 16 months ago after he injured his shoulder playing squash.
Cervical adenocarcinomas span a diverse group of tumors with several distinct histologic tumor types, which include endocervical (usual), endometrioid, intestinal, villoglandular, gastric, signet ring, clear cell, serous, and mesonephric.
M2 PHARMA-October 31, 2017-X4 Pharmaceuticals Completes Dose Escalation Portion of Clinical Trial of X4P-001-IO in Combination with Inlyta (Axitinib) in Patients with Clear Cell Renal Cell Carcinoma
Methods: We retrospectively studied 69 surgical RCC cases from August 2014 to February 2016, including 18 cases of clear cell RCC (ccRCC) demonstrating elevated pretreatment serum C-reactive protein (CRP, Group A).
We are pleased to expand our collaboration with Calithera into NSCLC and melanoma, building upon our existing clinical study evaluating Opdivo and CB839 in clear cell renal cell carcinoma," said Fouad Namouni, M.
2) We present our experience with three cases of clear cell RCC with metastases to the head and neck region.
Fine-needle aspiration cytology of the cutaneous nodules revealed a heterogeneous, clear cell population arranged in loose clusters and singles showing cytoplasmic vacuolation, high nuclear-cytoplasmic ratio.
M2 EQUITYBITES-February 14, 2017-ITC Service Group buys Clear Cell Management
TELECOMWORLDWIRE-February 14, 2017-ITC Service Group buys Clear Cell Management
14 February 2017 - California, US-based telecommunications service provider ITC Service Group, a subsidiary of Moorgate Capital Partners, has acquired substantially all of the assets of New Jersey, US-based wireless telecommunications service provider Clear Cell Management, Inc.