clean room

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A highly filtered environment used to manufacture and/or package sterile and high purity products—e.g., microprocessors, pharmaceuticals, and other dust or microbe-sensitive products—to protect personnel, equipment, and products from microbial contamination and to prevent the escape of hazardous substances into the environment

clean room

A controlled environment facility in which all incoming air passes through a filter capable of removing 99.97% of all particles 0.3μ m and larger. The temperature, pressure, and humidity in the room are controlled. Clean rooms are used in research and in controlling infections, esp. for persons who may not have normally functioning immune systems (e.g., individuals who have been treated with immunosuppressive drugs in preparation for organ transplantation).

In very rare instances a child is born without the ability to develop an immune system. Such children are kept in a clean room while waiting for specific therapy such as bone marrow transplantation.

See also: room
References in periodicals archive ?
Utilizing an ultrasonic cleaning as part of the pharmaceutical manufacturing process--either-for cleaning machinery prior the items entering the clean room, or in the clean room itself--can greatly improve a clean room's efficacy.
The silicone rubber moulded components go direct to the assembly line without leaving the clean room and all inspection, assembly and handling is self-contained.
Global Modular Systems builds affordable clean room facilities that are custom-made for their clients' most urgent of in-house demands.
Adding the clean rooms allows us to expand our capabilities for our pharmaceutical customers," said Tee Noland, PTI's director of business development.
Borrowing clean room technology usually reserved for high technology and medical research, frozen food giant Celentano has entered the home meal replacement market with a new product line of entrees and side dishes that promises to double the company's revenues in the next two years.
The filters pull so much air through them, Lebens says, that "if it goes on for years, it can ruin your whole clean room.
With the help of the SBA last October, Clean Rooms International purchased a 30,000 square foot facility so they can grow their operation and hire more employees.
Modular clean rooms are contamination-free environments for product production, research and other sensitive products and processes that require a completely sterile workspace.
Pharmaceutical clean rooms provide pharmaceutical manufacturers with a clean, safe environment in which to create uncontaminated products.
Arrow Medical's Kington contract medical manufacturing facility now includes three clean rooms, using solvent and UV curing adhesive assembly, manual and semi-automated lines for radio frequency welding, and multi-layer fabric assembly, including cutting and sewing.