clean room


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A highly filtered environment used to manufacture and/or package sterile and high purity products—e.g., microprocessors, pharmaceuticals, and other dust or microbe-sensitive products—to protect personnel, equipment, and products from microbial contamination and to prevent the escape of hazardous substances into the environment

clean room

A controlled environment facility in which all incoming air passes through a filter capable of removing 99.97% of all particles 0.3μ m and larger. The temperature, pressure, and humidity in the room are controlled. Clean rooms are used in research and in controlling infections, esp. for persons who may not have normally functioning immune systems (e.g., individuals who have been treated with immunosuppressive drugs in preparation for organ transplantation).

In very rare instances a child is born without the ability to develop an immune system. Such children are kept in a clean room while waiting for specific therapy such as bone marrow transplantation.

See also: room
References in periodicals archive ?
Utilizing an ultrasonic cleaning as part of the pharmaceutical manufacturing process--either-for cleaning machinery prior the items entering the clean room, or in the clean room itself--can greatly improve a clean room's efficacy.
Table 21: US Historic Review for Industrial Protective Clothing by Product Segment - Chemical Protection Clothing, Thermal Clothing, Clean Room Clothing and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2004 through 2009 (includes corresponding Graph/Chart) III-8
According to Gary Avalon, chief operating officer, the precision clean room facility satisfies marketplace preferences for goods that have been produced in a clean room environment.
The new facilities can supply components for complete medical device assembly services within all three clean rooms.
Global Modular Systems builds affordable clean room facilities that are custom-made for their clients' most urgent of in-house demands.
One half of the allotted embryos were randomized to the clean room laboratory and the other half to the andrology laboratory.
To reach the required ISO class 4 clean room standard an environment must have no more that ten particles of 0.
When it is used in a combination of an arm head and a clock head, it allows servo track writing without the use of a clean room.
The filters pull so much air through them, Lebens says, that "if it goes on for years, it can ruin your whole clean room.
Clean Room Products, Ronkonkoma, NY, recently introduced the "Ultra Clean Polypropylene Breather Bag" that is designed specifically for stopper and other component sterilization requiring a particle-free environment and minimum fomite generation.
headquarters in Strongsville, Ohio) developed a self-contained clean room integrating an IntElect 160-metric-ton, all-electric press, fully integrated six-axis robot, and a bagging system for parts.