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clastogenic |
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clastogenic /clas·to·gen·ic/ (klas″tah-jen´ik) causing disruption or breakages, as of chromosomes.
clastogenic giving rise to or inducing disruption or breakages, as of chromosomes. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Association between the clastogenic effect in peripheral lymphocytes and human exposure to arsenic through drinking water. Sitagliptin was not mutagenic or clastogenic with or without metabolic activation in the Ames bacterial mutagenicity assay, a Chinese hamster ovary (CHO) chromosome aberration assay, an in vitro cytogenetics assay in CHO, an in vitro rat hepatocyte DNA alkaline elution assay, and an in vivo micronucleus assay. Several possible mechanisms were considered, such as clastogenic damage to circulating stem cells. |
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