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clastogenic

   Also found in: Wikipedia 0.04 sec.
clastogenic /clas·to·gen·ic/ (klas?tah-jen´ik) causing disruption or breakages, as of chromosomes.
clas·to·gen·ic (klst-jnk)
adj.
Capable of causing breakage of chromosomes.
clastogenic
giving rise to or inducing disruption or breakages, as of chromosomes.
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Association between the clastogenic effect in peripheral lymphocytes and human exposure to arsenic through drinking water.
Dietary intake and arsenic methylation in a U.S. population by Smith, Allan H. / Environmental Health Perspectives
Sitagliptin was not mutagenic or clastogenic with or without metabolic activation in the Ames bacterial mutagenicity assay, a Chinese hamster ovary (CHO) chromosome aberration assay, an in vitro cytogenetics assay in CHO, an in vitro rat hepatocyte DNA alkaline elution assay, and an in vivo micronucleus assay.
FDA Accepts Two Supplemental New Drug Applications to Expand the U.S. ... by Business Wire
Several possible mechanisms were considered, such as clastogenic damage to circulating stem cells.
Meeting report: summary of IARC Monographs on formaldehyde, ... by El Ghissassi, Fatiha / Environmental Health Perspectives
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