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clastogenic |
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clastogenic /clas·to·gen·ic/ (klas?tah-jen´ik) causing disruption or breakages, as of chromosomes.
clastogenic giving rise to or inducing disruption or breakages, as of chromosomes. |
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? Mentioned in | ? References in periodicals archive | |
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| Association between the clastogenic effect in peripheral lymphocytes and human exposure to arsenic through drinking water. Sitagliptin was not mutagenic or clastogenic with or without metabolic activation in the Ames bacterial mutagenicity assay, a Chinese hamster ovary (CHO) chromosome aberration assay, an in vitro cytogenetics assay in CHO, an in vitro rat hepatocyte DNA alkaline elution assay, and an in vivo micronucleus assay. Several possible mechanisms were considered, such as clastogenic damage to circulating stem cells. |
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