and epigenetic effects of gold nanoparticles in mice.
The chemical diversity of these pollutants causes a variety of clastogenic
, mutagenic, carcinogenic endocrine effects on fishes and other aquatic communities in recipient water bodies (Karrasch et al.
The detection of micronuclei (MNi) has been widely used for years for the evaluation of mutagenic, clastogenic
and aneugenic effects in vivo and in vitro.
MN test provides a measure of both chromosome breakage and chromosome loss or nondisjunction in clastogenic
and aneugenic events (13).
Mutagenic and clastogenic
properties of 3-chloro-4-(dichloromethyl)-5-hydroxy2(5H)-furanone: A potent bacterial mutagen in drinking water.
Lab studies show that extracts of ginkgo biloba reduce the effects of clastogenic
factors--external materials (including plutonium and other radioactive substances) that fragment or delete DNA and inflict chromosomal damage, leading to mutation and cancer proliferation.
and aneugenic effects of tamoxifen and some of its analogues in hepatocytes from doses rats and in human lymphoblastoid cells transfected with human P450 cDNAs (MCL-5 cells).
Consequently, enumeration of micronuclei in the cytoplasm of the interphase daughter cell has been used to quantitate clastogenic
or aneugenic chromosome DNA damage [11,14].
potential of Ruta graveolens extract and a homeopathic preparation in mouse bone marrow cells.
Aeolian dune-hummocky relief was formed on sandy lowlands, especially in Polesye, and allochthonous clastogenic
material accumulated in primary lake reservoirs (Velichkevich et al.
and mutagenic activity of certain heavy metals in Allium cepa and Hordeum vulgare.
Rabbani SI, Devi K, Khanam S and N Zahra Citral a component of lemongrass oil inhibits the clastogenic
effect of nickel chloride in mouse micronucleus test system.