clastogenic


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clastogenic

 [klas″to-jen´ik]
giving rise to or inducing disruption or breakages, as of chromosomes.

clas·to·gen·ic

(klas'tō-jen'ik),
Relating to the action of a clastogen.

clastogenic

/clas·to·gen·ic/ (klas″tah-jen´ik) causing disruption or breakages, as of chromosomes.

clas·to·gen·ic

(klas-tō-jen'ik)
Relating to the action of a clastogen.

clastogenic

giving rise to or inducing disruption or breakages, as of chromosomes.
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References in periodicals archive ?
Most ADCs under clinical investigation contain cytotoxic agents that act by directly inducing DNA damage or exerting clastogenic effects.
Preliminary results on ascorbic acid and lysine suppression of clastogenic effect of deep-frozen sperm of the russian sturgeon (Acipenser gueldenstaedti).
Markers of genotoxicity, such as elevated levels of oxidized DNA nucleobases, bulky DNA adducts, and clastogenic end points in leukocytes have been documented in biomonitoring studies of humans.
In general, chromosome bridges and fragments indicated a clastogenic mechanism of action of the tested substance, with some activity related to genotoxicity (action on DNA structure).
2011), were clastogenic, mutagenic, and cytotoxic to normal human peripheral blood cells; boric acid, citric acid, potassium citrate and sodium citrate (Brasil, 1999) which, in agreement with Ttikoglu (2007), were cytotoxic to root meristems cells of A cepa.
A micronucleus technique for detecting clastogenic effects of mutagens/carcinogens in hepatocytes of rat liver in vivo.
These results indicate that ZnO nanorods at the current treatment conditions didn't cause clastogenic effect in mature erythrocytes (% MnNCEs).
Some authors also report medicinal properties associated with the consumption of rapadura, such as decreased pulmonary lesions associated with smoking, reduced clastogenic effects caused by arsenic, high antioxidant action and an anti-sclerotic function (Jaffe, 2012).
Clastogenic and aneugenic effects of three benzimidazole derivatives in the in vitro micronucleus test using human lymphocytes.