citrulline


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citrulline

 [sit-rul´ēn]
an alpha amino acid involved in the urea cycle.

ci·trul·line

(sit'rul-ēn), Avoid the mispronunciation citrul'line.
An amino acid formed from l-ornithine in the course of the urea cycle as well as a product in nitric oxide biosynthesis; also found in watermelon (Citrullus vulgaris) and in casein. Elevated in individuals with a deficiency of argininosuccinate synthetase or argininosuccinate lyase.

citrulline

/cit·rul·line/ (sit´rul-ēn) an alpha-amino acid involved in urea production; formed from ornithine and itself converted into arginine in the urea cycle.

citrulline

(sĭt′rə-lēn′)
n.
An amino acid, C6H13N3O3, originally isolated from watermelon, that is produced as an intermediate in the conversion of ornithine to arginine during urea formation in the liver.

citrulline

[sitrul′ēn]
Etymology: L, Citrullus, watermelon
an amino acid produced from ornithine during the urea cycle. It is subsequently transformed to arginine by the transfer of a nitrogen atom from aspartate.

ci·trul·line

(sit'rŭ-lēn)
An amino acid formed from l-ornithine in the course of the urea cycle as well as a product in nitric oxide biosynthesis; also found in watermelon (Citrullus vulgaris) and in casein. Levels elevated in people with a deficiency of argininosuccinate synthetase or argininosuccinate lyase.

citrulline

an alpha amino acid involved in the urea cycle.

citrulline phosphorylase
see ornithine carbamoyl transferase.
References in periodicals archive ?
Hot topics in postsmall bowel transplantation: noninvasive graft monitoring including stool calprotectin and plasma citrulline.
The purpose of this study was to investigate the combined supplementation of BCAA, arginine, and citrulline on endurance performance in two consecutive days in trained runners.
sup][31] In addition, we found that citrulline in urea cycle was also increased at the early stage after ASCP, but the exact mechanism of this effect need further study.
Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness.
17g of citrulline; an unpasteurised enriched watermelon juice (EWJ) with 6g of citrulline and a colour-similar placebo infusion of fruit-flavoured plants with a sugar content similar to the watermelon juices.
What's more, citrulline may have antioxidant properties that can protect the body from free-radical damage.
Watermelon is also a natural source of citrulline, a non-essential amino acid with various health and athletic performance benefits.
Watermelons are also high in citrulline, an amino acid which, "improves the cardiovascular and immune system and thus has beneficial effects on the health of the blood vessels," she says.
PADI4 (peptidylarginine deiminase type 4) polymorphisms, regulating PAD4 (peptidylarginine deiminase 4), an enzyme which is responsible for the formation of citrulline from arginine, have been identified in the Japanese population as a RA susceptibility Locus (53) and associated with anti-CCP antibodies.
Apart from its high moisture content, the fruit is a great fat burner that contains an unusual amino acid -- L- citrulline -- which boosts energy levels and reduces fatigue.
Plasma amino acid analysis revealed absence of citrulline and argininosuccinic acid, low normal ornithine, and high urinary orotic acid levels consistent with proximal urea cycle defects like Ornithine Transcarbamylase deficiency (OTC), N-acetyl Glutamate Synthase deficiency (NAGS), and Carbomyl Phosphate Synthase 1 deficiency (CPS1).
The results showed that there was a clear positive effect on the levels of citrulline in patients treated with ZP1848, compared to placebo.