citrulline


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citrulline

 [sit-rul´ēn]
an alpha amino acid involved in the urea cycle.

ci·trul·line

(sit'rul-ēn), Avoid the mispronunciation citrul'line.
An amino acid formed from l-ornithine in the course of the urea cycle as well as a product in nitric oxide biosynthesis; also found in watermelon (Citrullus vulgaris) and in casein. Elevated in individuals with a deficiency of argininosuccinate synthetase or argininosuccinate lyase.

citrulline

/cit·rul·line/ (sit´rul-ēn) an alpha-amino acid involved in urea production; formed from ornithine and itself converted into arginine in the urea cycle.

citrulline

(sĭt′rə-lēn′)
n.
An amino acid, C6H13N3O3, originally isolated from watermelon, that is produced as an intermediate in the conversion of ornithine to arginine during urea formation in the liver.

citrulline

[sitrul′ēn]
Etymology: L, Citrullus, watermelon
an amino acid produced from ornithine during the urea cycle. It is subsequently transformed to arginine by the transfer of a nitrogen atom from aspartate.

ci·trul·line

(sit'rŭ-lēn)
An amino acid formed from l-ornithine in the course of the urea cycle as well as a product in nitric oxide biosynthesis; also found in watermelon (Citrullus vulgaris) and in casein. Levels elevated in people with a deficiency of argininosuccinate synthetase or argininosuccinate lyase.

citrulline

an alpha amino acid involved in the urea cycle.

citrulline phosphorylase
see ornithine carbamoyl transferase.
References in periodicals archive ?
1990) demonstrated that the endogenous synthesis of Arg in the kidney depends on the synthesis of ornithine and citrulline in the intestine.
Cytochrome P450 catalyzes the oxidation of Nw-hydroxy-l-arginine by NADPH and 02 to nitric oxide and citrulline.
Citrulline is an amino acid that is also involved in the metabolic pathway of production of the endothelium-relaxing gas nitric oxide.
Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies.
Arginine or citrulline is often recommended to address those, and other, disorders.
Nitric oxide synthases (NOS) are a family of cysteine thiolate-ligated heme-containing monooxygenases that catalyze the NADPH-dependent two-step conversion of L-arginine to NO and citrulline.
Scientists have discovered that watermelons contain an amino acid called citrulline, which triggers the production of nitric oxide - the key to male performance.
Natural dietary substances that reduce the production of AGE proteins or the initiation of the UPR process inside neurons include arginine, citrulline and DHA, as well as those that provide antioxidant properties, including Ginkgo biloba extract.
One of the biggest milestones has been the recent research into the presence of citrulline in watermelon and its benefits for athletes.
1 is a schematic of the urea cycle and the common interventions, including driving the urea cycle with supplements of arginine or citrulline and by administering compounds such as sodium benzoate or sodium phenylacetate to form complexes with ammonia that can be excreted in the urine.
PAD changes residues of certain proteins into citrulline, and the body recognizes citullinated proteins as intruders, leading to an immune attack.