Effect of
citrinin, a mycotoxin produced by Penicillium citrinum on laying hens and young broiler chicks.
Synergistic effect of
cItrinin on hepatorenal carcinogenesis of ochratoxin A in mice.
Besides, species of Penicillium cause kidney disease in human and pigs due to production of the mycotoxin called
Citrinin [37].
One popular brand was also discovered to contain
citrinin, a potential kidney toxin, according to the report.
Scientific opinion on the risk for public and animal health related to the presence of
citrinin in food and feed.
Some of these minor mycotoxins include T-2 toxin, fusaric acid, cyclopiazeaic acid, patulin, gliotoxin,
citrinin, and ergot alkaloids.
Aspergillus terreus is associated with aspergillosis of the lungs and/or disseminated aspergillosis and can produce the toxins patulin and
citrinin, which may be associated with disease in humans and animals.
It appears that the production of polyketide azaphilone pigments from such potentially safe hosts is advantageous over traditional processes that involve Monascus, which risks co-production of the mycotoxin
citrinin.
And, as if that wasn't bad enough, four out of the 12 supplements tested had detectible amounts of
citrinin.
Exposure to staplabin and SMTP-7 alone decreased slightly, but not dose dependently, the viability of the macrophages, whereas ochratoxin,
citrinin, and sterigmatocystin did not cause excessive cell death alone or when combined with the spores of Str.
In addition these materials are tested for their resistance to colonization by both Trichoderma haematum and Penicillium
citrinin in the laboratory.
Our evaluation has insured that HPLC testing verified the monacolins to be within naturally occurring levels and further documented that
citrinin was not present in significant quantities in these products.