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tricarboxylic acid cycle
(redirected from citric-acid cycle)

   Also found in: Dictionary/thesaurus, Encyclopedia 0.01 sec.
cycle /cy·cle/ (si´k'l) a succession or recurring series of events.
carbon cycle  the steps by which carbon (in the form of carbon dioxide) is extracted from the atmosphere by living organisms and ultimately returned to the atmosphere. It comprises a series of interconversions of carbon compounds beginning with the production of carbohydrates by plants during photosynthesis, proceeding through animal consumption, and ending and beginning again in the decomposition of the animal or plant or in the exhalation of carbon dioxide by animals.
cardiac cycle  a complete cardiac movement, or heart beat, including systole, diastole, and intervening pause.
Enlarge picture
Events of the cardiac cycle.
cell cycle  the cycle of biochemical and morphological events occurring in a reproducing cell population; it consists of: the S phase, occurring toward the end of interphase, in which DNA is synthesized; the G2 phase, a relatively quiescent period; the M phase, consisting of the four phases of mitosis; and the G1 phase of interphase, which lasts until the S phase of the next cycle.
citric acid cycle  tricarboxylic acid c.
Cori cycle  the mechanism by which lactate produced by muscles is carried to the liver, converted back to glucose via gluconeogenesis, and returned to the muscles.
γ-glutamyl cycle  a metabolic cycle for transporting amino acids into cells.
hair cycle  the phases of the life of a hair, consisting of anagen, catagen, and telogen.
Krebs cycle  tricarboxylic acid c.
Krebs-Henseleit cycle  urea c.
menstrual cycle  the period of the regularly recurring physiologic changes in the endometrium, occurring during the reproductive period of female humans, culminating in partial shedding of the endometrium and some bleeding per vagina (menstruating).
Enlarge picture
Changes in the menstrual cycle in the human female. Solid lines indicate the course of events when the oocyte is not fertilized; dotted lines indicate the course of events when fertilization occurs. Arrows indicate the actions of hormones of the pituitary and the ovary in regulating the cycle.
mosquito cycle  that period in the life of a malarial parasite that is spent in the body of the mosquito host.
nitrogen cycle  the steps by which nitrogen is extracted from the nitrates of soil and water, incorporated as amino acids and proteins in living organisms, and ultimately reconverted to nitrates: (1) conversion of nitrogen to nitrates by bacteria; (2) the extraction of the nitrates by plants and the building of amino acids and proteins by adding an amino group to the carbon compounds produced in photosynthesis; (3) the ingestion of plants by animals, and (4) the return of nitrogen to the soil in animal excretions or on the death and decomposition of plants and animals.
ornithine cycle  urea c.
ovarian cycle  the sequence of physiologic changes in the ovary involved in ovulation.
reproductive cycle  the cycle of physiologic changes in the female reproductive organs, from the time of fertilization of the oocyte through gestation and parturition.
sex cycle , sexual cycle
1. the physiologic changes recurring regularly in the genital organs of nonpregnant female mammals; in humans, the menstrual cycle.
2. the period of sexual reproduction in an organism that also reproduces asexually.
tricarboxylic acid cycle  the final common pathway for the oxidation to CO2 of fuel molecules, most of which enter as acetyl coenzyme A; it also provides intermediates for biosynthetic reactions and generates ATP by providing electrons to the electron transport chain.
Enlarge picture
Tricarboxylic acid cycle. Diagrammatic representation of reactions by which carbon chains of sugars, fatty acids, and amino acids are metabolized to yield carbon dioxide. Water produced by the cycle and components of the high-energy phosphate pool generated by the associated electron chain are not shown.
urea cycle  a series of metabolic reactions in the liver, by which ammonia is converted to urea using cyclically regenerated ornithine as a carrier.
Enlarge picture
Urea cycle. Diagrammatic representation of reactions by which excess nitrogen in the form of ammonia is converted to soluble urea, using l-ornithine as a recyclable carrier.
uterine cycle  the phenomena occurring in the endometrium during the menstrual cycle, preparing it for implantation of the blastocyst.
visual cycle  the cyclic interconversion of 11-cis- retinal and all-trans- retinal and association with opsins, creating an electric potential and initiating the cascade generating a sensory nerve impulse in vision.
Enlarge picture
Visual cycle of retinal rod cells; an analogous cycle occurs with iodopsins in the cones.

tri·car·box·yl·ic acid cycle (trkär-bk-slk)
n.

tricarboxylic acid cycle.
cycle [si´k'l]
a succession or recurring series of events.
cardiac cycle a complete cardiac movement, or heart beat, including systole, diastole, and the intervening pause.
Cardiac cycle. From Applegate, 2000.
cell cycle the cycle of biochemical and morphological events occurring in a reproducing cell population; it consists of the S phase, occurring toward the end of interphase, in which DNA is synthesized; the G2 phase, a relatively quiescent period; the M phase, consisting of the four phases of mitosis; and the G1 phase of interphase, which lasts until the S phase of the next cycle.
citric acid cycle tricarboxylic acid cycle.
estrous cycle the recurring periods of estrus in adult females of most mammalian species and the correlated changes in the reproductive tract from one period to another.
hair cycle the successive phases of the production and then loss of hair, consisting of anagen, catagen, and telogen.
menstrual cycle see menstrual cycle.
ovarian cycle the sequence of physiologic changes in the ovary involved in ovulation; see also ovulation and reproduction.
reproductive cycle the cycle of physiologic changes in the reproductive organs, from the time of fertilization of the ovum through gestation and childbirth; see also reproduction.
sex cycle (sexual cycle)
1. the physiologic changes that recur regularly in the reproductive organs of nonpregnant female mammals.
2. the period of sexual reproduction in an organism that also reproduces asexually.
tricarboxylic acid cycle the cyclic metabolic mechanism by which the complete oxidation of the acetyl portion of acetyl-coenzyme A is effected; the process is the chief source of mammalian energy, during which carbon chains of sugars, fatty acids, and amino acids are metabolized to yield carbon dioxide, water, and high-energy phosphate bonds. Called also citric acid cycle, Krebs cycle, and TCA cycle.
 Central pathways of metabolism: How the body produces energy from the energy-containing nutrients using the tricarboxylic acid cycle. From Davis and Sherer, 1994.
urea cycle a cyclic series of reactions that produce urea; it is a major route for removal of the ammonia produced in the metabolism of amino acids in the liver and kidney.

tricarboxylic acid cycle
the cyclic metabolic mechanism by which the complete oxidation of the acetyl moiety of acetyl-coenzyme A is effected; abbreviated TCA cycle. It is the chief source of mammalian energy, during which acetyl groups derived from the metabolism of sugars, fatty acids and amino acid are oxidized to yield carbon dioxide, water and reduced coenzymes. Called also Krebs cycle and citric acid cycle.

cycle, Krebs 
A series of reactions in which the intermediate products of carbohydrate, fat and protein metabolism are converted to carbon dioxide and hydrogen atoms (electrons and hydrogen ions). This cycle can only operate in the presence of oxygen. Further oxidation yields carbon dioxide, water and ATP. This cycle occurs in the mitochondria that are found in the cytoplasm of cells of living organisms. It forms one of the processes in the metabolism of glucose providing energy (stored in ATP) to maintain the vital functions of the cells (e.g. mitosis). This cycle represents the principal energy pathway of the corneal endothelium. Syn. citric acid cycle; tricarboxylic acid cycle. See mitosis.
Table C9 Relationship between the minimum angle of resolution, the Snellen fraction and the equivalent spatial frequency of a sine wave
Snellen fraction
resolution (min of
arc)
(m)(ft)Spatial frequency (cpd)
0.56/320/1060
0.66/3.620/1250
0.756/4.520/1540
1.06/620/2030
1.256/7.520/2524
1.56/920/3020
2.06/1220/4015
2.56/1520/5012
4.06/2420/807.5
5.06/3020/1006
8.06/4820/1603.8
10.06/6020/2003
20.06/12020/4001.5

tricarboxylic acid cycle
Citric acid cycle, see there


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