citrated plasma

Also found in: Dictionary, Thesaurus, Encyclopedia.


1. the fluid portion of the lymph.
2. the fluid portion of the blood, in which the formed elements (blood cells) are suspended. Plasma is to be distinguished from serum, which is plasma from which the fibrinogen has been separated in the process of clotting. Called also blood plasma. adj., adj plasmat´ic, plas´mic.

Of the total volume of blood, 55 per cent is made up of plasma. It is a clear, straw-colored liquid, 92 per cent water, in which are contained plasma proteins, inorganic salts, nutrients, gases, waste materials from the cells, and various hormones, secretions, and enzymes. These substances are transported to or from the tissues of the body by the plasma.

Plasma obtained from blood donors is given to persons suffering from loss of blood or from shock to help maintain adequate blood pressure. Since plasma can be dried and stored in bottles, it can be transported almost anywhere, ready for immediate use after addition of the appropriate fluid. Plasma can be given to anyone, regardless of blood type. (See also transfusion.)

Plasma volume is sometimes measured in order to calculate the total blood volume. The most common method for determining plasma volume is by injection of a dye (T-1824, called Evans blue) into the circulating blood and, after the dye has been dispersed throughout the body, using the dilution of the dye to calculate the total blood volume.
antihemophilic human plasma normal human plasma that has been processed promptly to preserve the antihemophilic properties of the original blood; used for temporary correction of bleeding tendency in hemophilia.
blood plasma plasma (def. 2).
citrated plasma blood plasma treated with sodium citrate, which prevents clotting.
plasma exchange the removal of plasma from withdrawn blood (plasmapheresis) and retransfusion of the formed elements and type-specific fresh frozen plasma into the donor; done for removal of circulating antibodies or abnormal plasma components.
fresh frozen plasma plasma separated from whole blood and frozen within 8 hours; it contains all the coagulation factors.
plasma thromboplastin antecedent deficiency hemophilia C.

citrated plasma

Plasma from blood collected and mixed with sodium citrate, which prevents clotting. Citrated plasma is most often used for coagulation testing.
References in periodicals archive ?
Given the improved functional sensitivity and the independence of the peptide antagonist AE120, we conclude that TR-FIA 4 is superior to TR-FIA 3 for measuring uPAR(I) in citrated plasma.
TR-FIA 2 measures free intact uPAR and uPAR(II-III), and the suPAR concentrations in donor citrated plasma obtained with these 2 assays are similar (8).
GDF15 concentrations were determined in citrated plasma samples from 429 apparently healthy elderly individuals included in the population-based SWISCH study (26).
We obtained virtually identical results with a sample of citrated plasma from another CHF patient (data not shown).
The mean ISI for the whole-blood and citrated plasma calibrations were compared by use of paired t-tests and 95% confidence intervals (CIs).
Citrated plasmas from these same blood samples were then tested in parallel with the conventional manual PT method and ECAA rabbit reference thromboplastin.
The MNPTs (geometric mean of the PTs obtained for the 20 samples from healthy blood donors) for whole blood and citrated plasma were compared using paired t-tests on the log PT obtained for the healthy blood donors, for the three centers, and for the three monitoring systems.
Human citrated plasma was diluted 1:1 with 50 mmol/L phosphate buffer, pH 7.
Because addition of citrate solution to the blood diluted the plasma, the D-Dimer concentrations in citrated plasma were lower than in heparinized plasma (found median difference was 16%, which corresponded to an estimated plasma fraction of 58%, or a 42% hematocrit).
r] = 75 000) and TGF-[beta] (MT = 25 000) are identical and equal to the mean concentration of latent TGF-[beta] found in citrated plasma, i.
The PIOP/dry chemistry technology may be used with whole blood or citrated plasma, yielding similar results for most tests.
According to Affinity Biologicals, “The VisuDep-F Frozen Factor VIII Deficient Plasma is intended for use as a substrate plasma in the quantitative determination of Factor VIII activity in citrated plasmas using a clot-based assay.