citrated plasma


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plasma

 [plaz´mah]
1. the fluid portion of the lymph.
2. the fluid portion of the blood, in which the formed elements (blood cells) are suspended. Plasma is to be distinguished from serum, which is plasma from which the fibrinogen has been separated in the process of clotting. Called also blood plasma. adj., adj plasmat´ic, plas´mic.

Of the total volume of blood, 55 per cent is made up of plasma. It is a clear, straw-colored liquid, 92 per cent water, in which are contained plasma proteins, inorganic salts, nutrients, gases, waste materials from the cells, and various hormones, secretions, and enzymes. These substances are transported to or from the tissues of the body by the plasma.

Plasma obtained from blood donors is given to persons suffering from loss of blood or from shock to help maintain adequate blood pressure. Since plasma can be dried and stored in bottles, it can be transported almost anywhere, ready for immediate use after addition of the appropriate fluid. Plasma can be given to anyone, regardless of blood type. (See also transfusion.)

Plasma volume is sometimes measured in order to calculate the total blood volume. The most common method for determining plasma volume is by injection of a dye (T-1824, called Evans blue) into the circulating blood and, after the dye has been dispersed throughout the body, using the dilution of the dye to calculate the total blood volume.
antihemophilic human plasma normal human plasma that has been processed promptly to preserve the antihemophilic properties of the original blood; used for temporary correction of bleeding tendency in hemophilia.
blood plasma plasma (def. 2).
citrated plasma blood plasma treated with sodium citrate, which prevents clotting.
plasma exchange the removal of plasma from withdrawn blood (plasmapheresis) and retransfusion of the formed elements and type-specific fresh frozen plasma into the donor; done for removal of circulating antibodies or abnormal plasma components.
fresh frozen plasma plasma separated from whole blood and frozen within 8 hours; it contains all the coagulation factors.
plasma thromboplastin antecedent deficiency hemophilia C.

citrated plasma

Plasma from blood collected and mixed with sodium citrate, which prevents clotting. Citrated plasma is most often used for coagulation testing.
References in periodicals archive ?
Surprisingly, we found that conjugated bilirubin slightly prolonged aPTT in citrated plasma, and more prominent prolongation was observed in heparinized samples.
Because the observations of increased antithrombin levels during warfarin therapy were made in patients with congenital partial deficiencies of antithrombin, we would have liked to test this patient population with an amidolytic assay using a citrated plasma specimen.
The measured FSTL1 concentrations in citrated plasma and heparin-treated plasma were somewhat lower than concentrations measured in serum or EDTA-treated plasma.
The Clauss method measures the rate of clot formation after adding a high concentration of thrombin to citrated plasma.
We loaded serum and citrated plasma samples (1 mL) from 2 patients with CHF onto the column and collected the eluate in 95 60-drop fractions.
The ISIs for whole blood and citrated plasma with the three monitoring systems were derived according to the conventional WHO orthogonal regression procedure (1, 2).
Control plasma was obtained by pooling citrated plasma from 10 healthy volunteers.
Heparin was the preferred anticoagulant because the elution peak of allantoin was completely masked when EDTA-treated or citrated plasma was used (results not shown)
The internal quality control was citrated plasma (time-expired, fresh-frozen plasma; West Midlands Blood Transfusion Service) with HCySH added at 8.
Precision of the assays was evaluated with three pools of citrated plasma obtained from patients (n [greater than or equal to] 10) with low, medium, and high D-Dimer content, respectively (Table 1).