cisplatinum


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cisplatinum

(sĭs-plăt′n-əm)
n.

Patient discussion about cisplatinum

Q. Is pervasive developmental disorder (PDD) or autism is fatal……what exactly it is……?

A. Autism is not fatal in its symptom and progression but it can become fatal as it does impair normal physiological function it CAN BE a fatal condition. It’s a group of illness which involves delays in the development of basic skills. It happens to children below age 3. It affects the child`s ability to communicate and interact. Autism affected children are also found to be mentally retarded.

Q. I was at my colleague's home and one of his kids kept talking to herself he said that she has PDD. i later asked my wife about it and she said she thinks it's a type of autism. but other than talking to herself the girl seemed perfectly normal. so is PDD a light version of autism?

A. I didn't really understand everything in this web page, but I think I get the big picture. Thanx

Q. What resources are available in Seattle, Washington to help with an autistic child?

A. i miss Seattle... here is a link to "Autism Spectrum Treatment and Research (ASTAR) Center". a well know establishment:

http://www.astarcenter.org/

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Patient characteristics and outcomes of treatment Case Age Sex Chemotherapy Surgical details 1 8 F PLADO R hepatectomy Clear margins 2 5 F VIDE R hepatectomy Clear margins Spillage 3 6 F VIDE R hepatectomy Clear margins Spillage 4 8 F Declined Partial hepatectomy Excision of part of diaphragm Residual disease 5 11 M VIDE R hepatectomy spontaneous rupture Case Additional information Follow up Status 1 15 years NED 2 21 months LTFU 3 Second look surgery: cyst 39 months NED removed 4 18 months DOD 5 Recurrence treated 12 months DOD with brachytherapy radiation PLADO = cisplatinum and doxorubicin; VIDE = vincristine, ifosfamide, doxorubicin, etoposide; NED = no evidence of disease; LTFU = lost to follow up; DOD = died of disease.
Neoadjuvant cisplatinum based combination chemotherapy in patients with invasive bladder cancer: A combined analysis of two Nordic studies.
Of the resections for malignancy, 9 were for hepatoblastomas, following cisplatinum and doxorubicin neoadjuvant chemotherapy.
In in vivo studies, the efficacy of EP-100 in comparison to saline or unconjugated CLIP 71 or cisplatinum in an ovarian cancer xenograft model (OVCAR-3) was studied.
In view of the presence of both an adenocarcinoma and an acinic cell carcinoma at the surgical margins, she underwent 3,000 cGy of radiation therapy and 3 courses of chemotherapy with 5-fluorouracil and cisplatinum.
At present, studies are comparing surgery with epirubicin, cisplatinum, and 5-FU pre- and postoperatively because this therapy appears to be more effective than 5-FU/leucovorin alone (99).
She is currently receiving combination chemotherapy with cisplatinum and doxorubicin.
Dacarbazine, carmustine, and cisplatinum have shown single-agent tumor responses in up to 25% of cases.
Much impetus derived from a study of 85 women within Cancer and Leukemia Group B (CALGB) involving the use of high-dose cyclophosphamide, cisplatinum, and carmustine [Solid Tumor Autologous Marrow Transplant Program (STAMP) I regimen] as consolidation after an intensive regimen of cyclophosphamide, doxorubicin, and 5-fluorouracil in CALGB 8782 (69,70).
The partial response occurred in a 62-year-old woman with N-cadherin positive squamous cell cancer of the esophagus and lung metastases, which had been unresponsive to prior treatment with cisplatinum and 5-fluorouracil chemotherapy, and who was subsequently treated with Exherin(TM).
The study will evaluate MORAb-009, plus the chemotherapy drugs pemetrexed and cisplatinum, as a first-line treatment for patients with mesothelioma.
Cisplatinum is quite reliably ototoxic, but individual sensitivity varies.