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cis-platinum

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cisplatin, cis-platinum
a platinum-containing complex used as an antineoplastic agent whose main mode of action resembles that of alkylating agents—production of cross-links between the two strands of DNA in the double helix so that DNA cannot be replicated and the cells cannot divide.
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Carter brings to the Telik drug development team extensive successful pharmaceutical industry experience in the development and approval of novel cancer drugs, including taxol and cis-platinum, which are currently two of the most important drugs for cancer treatment," said Michael M.
Telik Announces Appointment of Stephen K. Carter, M.D. to Scientific ... by Business Wire
Importantly, cross-resistance to the clinically important drugs adriamycin, cis-platinum, and taxol did not occur in cell lines that were resistant to TLK286.
Telik Announces Presentation of Additional Data Describing Mechanism ... by Business Wire
For example, cis-platinum, one of the most widely used anti-cancer drugs, caused renal failure before the importance of hydration and diuretics was understood.
NeoRx Suspends Accrual on its STR Trials Pending Resolution with FDA; ... by Business Wire
 
 
 
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