ciprofloxacin


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Related to ciprofloxacin: metronidazole

ciprofloxacin

 [sip″ro-flok´sah-sin]
a quinolone antibacterial agent effective against many gram-positive and gram-negative bacteria, including some strains resistant to other agents such as penicillins.

ciprofloxacin

/cip·ro·flox·a·cin/ (sip″ro-flok´sah-sin) a synthetic antibacterial effective against many gram-positive and gram-negative bacteria; used as the hydrochloride salt.

ciprofloxacin

(sĭp′rō-flŏk′sə-sĭn)
n.
A semisynthetic analog of fluoroquinolone that is administered orally and has a broad spectrum of antibiotic activity.

ciprofloxacin

Cipro® Antibiotics A broad-spectrum–GNRs, staphylococci, fluoroquinolone with limited activity against streptococci, anaerobes Indications Acute sinusitis, acute exacerbation of chronic bronchitis, UTI, acute cystitis in ♀, bacterial prostatitis, intra-abdominal infection, skin, bone and joint infection, infectious diarrhea, typhoid fever, gonorrhea Adverse effects GI pain, N&V, diarrhea, seizures, rash, photosensitivity. See Fluoroquinolone.

ciprofloxacin

A fluoroquinolone antibiotic used to treat urinary infections and, as eye drops, for the treatment of corneal ulcers. The drug acts by binding to the enzyme gyrase. Mutations lead to an alteration in the structure of this enzyme leading to antibiotic resistance. Current research suggests the possibility of preventing this process. The drug is on the WHO official list. Brand names are Ciproxin and Ciloxan.

ciprofloxacin

; Ciproxin quinolone antibacterial agent active against Gram-positive and Gram-negative bacteria, Pseudomonas and some mycobacteria

antibiotic 

1. Pertaining to the ability to destroy or inhibit other living organisms.
2. A substance derived from a mould or bacterium, or produced synthetically, that destroys (bactericidal) or inhibits the growth (bacteriostatic) of other microorganisms and is thus used to treat infections. Some substances have a narrow spectrum of activity whereas others act against a wide range of both gram-positive and gram-negative organisms (broad-spectrum antibiotics). Antibiotics can be classified into several groups according to their mode of action on or within bacteria: (1) Drugs inhibiting bacterial cell wall synthesis, such as bacitracin, vancomycin and the β-lactams based agents (e.g. penicillin, cephalosporins (e.g. ceftazidime, ceftriaxone, cefuroxime). (2) Drugs affecting the bacterial cytoplasmic membrane, such as polymyxin B sulfate and gramicidin. (3) Drugs inhibiting bacterial protein synthesis, such as aminoglycosides (e.g. amikacin sulfate, framycetin sulfate, gentamicin, neomycin sulfate and tobramycin), tetracyclines, macrolides (e.g. erythromycin and azithromycin) and chloramphenicol. (4) Drugs inhibiting the intermediate metabolism of bacteria, such as sulfonamides (e.g. sulfacetamide sodium) and trimethoprim. (5) Drugs inhibiting bacterial DNA synthesis, such as nalixidic acid and fluoroquinolones (e.g. ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin). (6) Other antibiotics such as fusidic acid, the diamidines, such as propamidine isethionate and dibrompropamidine. Syn. antibacterial. See antiinflammatory drug; fusidic acid.

ciprofloxacin,

n brand name: Cipro;
drug class: fluoroquinolone antiinfective;
action: a broad-spectrum bactericidal agent that inhibits enzyme deoxyribonucleic acid (DNA) gyrase needed for replication of DNA;
uses: adult urinary tract infection, uncomplicated gonorrhea, typhoid fever; effective against some periodontal organisms.

ciprofloxacin

a fluoroquinolone antibiotic with particularly good activity against gram-negative bacteria, including Enterobacteriaceae and Pseudomonas aeruginosa. It is used mainly in urinary tract infections.
References in periodicals archive ?
Percentages of elevated MICs for azithromycin were highest for isolates acquired in regions that had concurrent high proportions of isolates with decreased susceptibility or resistance to ciprofloxacin (Table).
sonnei infection, of which 24 were ciprofloxacin resistant.
Drug resistance of Pseudomonas to ciprofloxacin is an emerging problem.
The reason for the initiation of ciprofloxacin treatment in the evaluated patients was isolation of a ciprofloxacin-only susceptible pathogen in seven patients, prior antibiotic treatment failure in six patients (detailed data regarding the antibiotic agents administered prior to ciprofloxacin are presented in Table 1), and pre-emptive treatment in three patients with severe clinical manifestations.
A week later he presented to the emergency room with chills, fever, dysuria and increased urinary frequency and was placed on ciprofloxacin 500 mg orally twice a day.
03 g/kg per day, every 2 days 1 injection) for one month and ciprofloxacin (7 mg/kg per day, i.
In contrast to those data, ciprofloxacin resistance in 2001 showed up in less than 1 percent of gonorrhea infections in heterosexual men and in fewer than 2 percent of infections in men who have sex with men.
Patients receiving ciprofloxacin did not demonstrate any significant change in the longest QTc interval or mean QTc interval.
The objective of this investigation is to identify the major degradation products of ciprofloxacin in eye drop preparations when placed in natural sunlight.
Furthermore, ciprofloxacin and ceftriaxone are each given in a single dose, whereas rifampin is given twice daily for 2 days.
A new once-daily extended-release formulation of ciprofloxacin that could enhance treatment compliance was as safe and effective as conventional twice-daily ciprofloxacin for the treatment of complicated urinary tract infections and acute uncomplicated pyelonephritis in a recent study.
Alternatively, ciprofloxacin was used with some early success, but unfortunately, many strains of MRSA have become resistant to ciprofloxacin, and empirical use of this antibiotic without laboratory confirmation of its effectiveness can be dangerous.