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cinacalcet

   Also found in: Wikipedia 0.01 sec.
cinacalcet,
a calcium receptor agonist that directly lowers parathyroid hormone levels by increasing sensitivity of calcium-sensing receptors to extracellular calcium.
indications This drug is used to treat hypercalcemia in parathyroid carcinoma and secondary hyperparathyroidism in chronic kidney disease requiring dialysis.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Adverse effects of this drug include dizziness, hypertension, nausea, diarrhea, vomiting, anorexia, access infection, noncardiac chest pain, asthenia, and myalgia.


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Cinacalcet, a drug that has been linked to reducing bone loss in patients with kidney disease, is in its third phase of clinical trials.
Biovitrum will also have co-promotion rights in the Nordic region for all products developed under the agreement as well as for Amgen's cinacalcet hydrochloride, a treatment for some hyperparathyroid conditions, and palifermin, a therapy for treating chemotherapy-related inflammations of the mouth.
Cinacalcet would also likely receive reimbursement under the new Medicare bill, as it helps reduce bone loss in patients with kidney disease, Lund said.
 
 
 
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