ciclosporin


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Related to ciclosporin: tacrolimus

ciclosporin

ciclosporin (cyclosporine) 

An immunosuppressant used in the treatment of the ocular manifestation of autoimmune diseases, uveitis, scleritis, keratoconjunctivitis sicca, ligneous conjunctivitis, and to prevent rejection of corneal grafts, etc. It is believed to exert its immunosuppressive effect by inhibiting the activation of cytotoxic T-lymphocytes. See immunosuppressants.
References in periodicals archive ?
Ciclosporin microemulsion 100 mg / ml oral solution 50 ml bottle.
Successful treatment of collapsing focal segmental glomerulosclerosis with a combination of rituximab, steroids and ciclosporin.
Fujita said he was inspired by the discovery of ciclosporin, also derived from a fungus, which spurred research into how the immune system may be subdued in transplant patients.
Ideally such analyses should be based on comparisons with other treatments for severe chronic disease--azathioprine, methotrexate, ciclosporin, retinoids and oral corticosteroids.
Grapefruit juice should also be avoided if you take ciclosporin, terfenadine, vardenafil or sirolimus.
Three medicines are used for treating an acute attack: Aminosalicylates (such as balsalazide, mesalazine, olsalazine, sulfasalazine), Corticosteroids (budesonide, hydrocortisone, prednisolone) and Immunosuppressants (azathioprine, ciclosporin, mercaptopurine) Rest is important during an attack to allow healing to take place.
Positive response to masitinib was evident for dogs resistant or intolerant to ciclosporin and/or corticosteroids, and dogs with severe pruritus; two populations with high unmet medical need
is the first and only topical ciclosporin preparation licensed for the treatment of severe keratitis in patients with dry eye disease in the UK.
To control inflammation, particularly following an excisional or therapeutic penetrating keratoplasty, topical ciclosporin A or systemic ciclosporin may be used.
Tacrolimus versus microemulsified ciclosporin in liver transplantation: the TMC randomised controlled trial.
In the treatment of severely affected patients, topical therapy with vitamin D3 analogues demonstrated synergistic effects with UV phototherapy and systemic ciclosporin therapy.