cicatricial alopecia


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alopecia

 [al″o-pe´shah]
loss of hair; baldness. The cause of simple baldness is not yet fully understood, although it is known that the tendency to become bald is limited almost entirely to males, runs in certain families, and is more common in certain racial groups than in others. Baldness is often associated with aging, but it can occur in younger men. minoxidil has been approved as a topical treatment for male pattern baldness. Approximately one-third of the men undergoing this therapy have experienced hair regrowth. The effects of the drug take several months to develop and new hair growth may be limited; the hair is lost if treatment is discontinued. Hair transplants are also available to selected patients. Many men opt for no treatment.

Alopecia as an outcome of chemotherapy for a malignancy can be very distressing. The loss of hair usually is temporary and the hair will grow back after the course of treatment is completed. Male patients may feel more comfortable wearing a hat or cap when out in public. Female patients who wish to wear a wig are encouraged to obtain one that is lightweight and the same color as their hair. Having a hairdresser cut the wig to the patient's usual hair style can increase self-esteem. A kerchief or head scarf can be worn around the house if it is more comfortable than a wig. Receipts for wigs, hairpieces, and other headcovering should be saved; they are tax-deductible medical expenses when related to chemotherapy.
androgenetic alopecia (alopecia androgene´tica) a progressive, diffuse, symmetric loss of scalp hair. In men it begins in the twenties or early thirties with hair loss from the crown and the frontal and temple regions, ultimately leaving only a sparse peripheral rim of scalp hair (male pattern alopecia or male pattern baldness). In females it begins later, with less severe hair loss in the front area of the scalp. In affected areas, the follicles produce finer and lighter terminal hairs until terminal hair production ceases, with lengthening of the anagen phase and shortening of the telogen phase of hair growth. The cause is unknown but is believed to be a combination of genetic factors and increased response of hair follicles to androgens.
alopecia area´ta hair loss in sharply defined areas, usually the scalp or beard.
alopecia ca´pitis tota´lis loss of all the hair from the scalp.
cicatricial alopecia (alopecia cicatrisa´ta) irreversible loss of hair associated with scarring, usually on the scalp.
congenital alopecia (alopecia congenita´lis) congenital absence of the scalp hair, which may occur alone or be part of a more widespread disorder.
alopecia limina´ris hair loss at the hairline along the front and back edges of the scalp.
male pattern alopecia see androgenetic a.
moth-eaten alopecia syphilitic alopecia involving the scalp and beard and occurring in small, irregular scattered patches, resulting in a moth-eaten appearance.
symptomatic alopecia (alopecia symptoma´tica) loss of hair due to systemic or psychogenic causes, such as general ill health, infections of the scalp or skin, nervousness, or a specific disease such as typhoid fever, or to stress. The hair may fall out in patches, or there may be diffuse loss of hair instead of complete baldness in one area.
alopecia tota´lis loss of hair from the entire scalp.
alopecia universa´lis loss of hair from the entire body.

scar·ring al·o·pe·ci·a

alopecia in which hair follicles are irreversibly destroyed by scarring processes including trauma, burns, lupus erythematosus, lichen planopilaris, scleroderma, folliculitis decalvans, or of uncertain cause (pseudopelade).

cicatricial alopecia

[sisətrish′əl]
a form of baldness produced by scar formation in dermatoses such as lupus erythematosus, usually progressing to permanent baldness.

scar·ring al·o·pe·ci·a

(skahr'ing al'ō-pē'shē-ă)
Skin condition in which hair follicles are irreversibly destroyed by scarring processes including trauma, burns, lupus erythematosus, lichen planopilaris, scleroderma, folliculitis decalvans, or of uncertain cause (pseudopelade).
Synonym(s): cicatricial alopecia.
References in periodicals archive ?
Among 23 patients with undiagnosed disorders, 7 had traction folliculitis/alopecia; 7 had cicatricial alopecia, 4 had seborrheic dermatitis, 3 had female pattern hair loss, 1 had lichen planopilaris, and 1 had chemical breakage.
DIFFERENTIAL DIAGNOSIS: Tufted Folliculitis is an easily missed entity as it mimics various dermatological conditions that lead to cicatricial alopecia.
Cicatricial alopecia causes bald patches due to destruction of hair follicles and replaces with scar tissue.
The CARF Diamond Affair commences with an informal roundtable discussion luncheon on cicatricial alopecia with expert doctor and patient exchange.
But those structures are nonspecific, end-stage features of many different cicatricial alopecias, including lichen planopilaris, central centrifugal cicatricial alopecia, and even lupus.
Caption: In this case of inflammatory cicatricial alopecia with clinical findings of erythema, perifollicular scale, and early polytrichia, a biopsy was done within the marked area, which was diagnostic of lichen planopilaris.
Graham-Little-Piccardi-Lasseur syndrome, cicatricial alopecia, lichen planopilaris.
Graham-Little-Piccardi-Lassueur syndrome (GLPLS) is a rare variant of follicular lichen planus characterized by a triad cicatricial alopecia of scalp, non cicatricial alopecia of axilla and groin, along with follicular lichen planus of limbs and trunk.
CCCA is a subcategory of primary inflammatory cicatricial alopecia and is the most common form of scarring alopecia in any population that includes a significant number of black patients.
Patients and methods A study of 40 patients was conducted to study the clinical variants and histopathology of cicatricial alopecia.
3,4 It is considered an important cause of cicatricial alopecia of scalp and perifollicular erythema at the periphery of lesion is an important diagnostic clue.
Two lymphocytic cicatricial alopecias, lichen planopilaris and frontal fibrosing alopecia (FFA), have been associated with peroxisome proliferator-activated receptor gamma (PPARG) deficiency.