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chymase

   Also found in: Wikipedia 0.01 sec.
chymase
[kī′mās]
a serine proteinase present in human mast cells, most prominent in skin and connective tissue, where it can cleave angiotensin and stimulate mucous glands.


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Some of the mediators are histamine, heparin, leukotrienes, serotonin, chemotactic factors, tryptase, chymase and prostaglandins.
Recent evidence has revealed that skin mast cells and mast cell chymase are important for the formation of granulation tissue and the synthesis of collagen fibers that occur at the edge of the wound in the burn-healing model in mice [9].
Preformed mediators stored in cytoplasmic granules include histamine, tryptase, proteoglycans, chymase, carboxypeptidase A, and heparin.
 
 
 
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