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chymase |
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chymase [kī′mās] a serine proteinase present in human mast cells, most prominent in skin and connective tissue, where it can cleave angiotensin and stimulate mucous glands. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Preformed mediators stored in cytoplasmic granules include histamine, tryptase, proteoglycans, chymase, carboxypeptidase A, and heparin. Release of the mucosal mast cell granule chymase, rat mast cell protease II, during anaphylaxis is associated with the rapid development of paracellular permeability to macromolecules in rat jejunum. If this becomes known, he observes, "then a whole host of pharmacological agents that act on cells that produce chymase will become useful in treating EB. |
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