chylomicron


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Related to chylomicron: Chylomicron Retention Disease

chylomicron

 [ki″lo-mi´kron]
a particle of the class of lipoproteins responsible for the transport of exogenous cholesterol and triglycerides from the small intestine to tissues after meals. Chylomicrons are spherical particles with a core of triglycerides surrounded by a layer of phospholipids, cholesterol, and apolipoproteins.

chy·lo·mi·cron

, pl.

chy·lo·mi·cra

,

chy·lo·mi·crons

(kī'lō-mī'kron, -mī'kră, -mi'kronz),
A large lipid droplet (up to 100 mm in diameter) of reprocessed lipid synthesized in epithelial cells of the small intestine and containing triacylglycerols, cholesterol esters, and several apolipoproteins (for example, A-I, B-48, C-I, C-II, C-III, E); the least dense (less than 1.006 g/mL) of the plasma lipoproteins that function as transport vehicles.
[chylo- + G. micros, small]

chylomicron

/chy·lo·mi·cron/ (-mi´kron) a class of lipoproteins that transport exogenous (dietary) cholesterol and triglycerides after meals from the small intestine to tissues for degradation to chylomicron remnants.

chylomicron

(kī′lō-mī′krŏn′)
n.
A lipoprotein formed in the small intestine that transports dietary fats and cholesterol through the lymphatic system to the bloodstream. Chylomicrons are larger and less dense than very-low-density lipoproteins.

chylomicron

[kī′lōmī′kron]
Etymology: Gk, chylos + mikros, small
minute lipoproteins measuring less than 0.5 μm in diameter. Chylomicrons consist of about 90 triglycerides with small amounts of cholesterol, phospholipids, fat-soluble vitamins, and protein. They are synthesized in the GI tract and carry dietary fat from the intestinal mucosa via the thoracic lymphatic duct into the plasma and ultimately to the liver and tissues. The remnant chylomicron particles are removed by the liver.

chy·lo·mi·cron

, pl. chylomicra, pl.chylomicrons (kī'lō-mī'kron, -kră,-kronz)
A droplet of reprocessed lipid synthesized in epithelial cells of the small intestine; the least dense of the plasma lipoproteins.
[chylo- + G. micros, small]

chylomicron

the form in which fat is transported from the gut to the rest of the body, consisting of a lipid core surrounded by an envelope of protein, cholesterol and phospholipid. Chylomicrons are around 100 nm across and are formed in the intestinal mucosa, from where they enter the LACTEALS and eventually the bloodstream.

chylomicron

a stable droplet containing principally triglyceride fat, but also cholesterol, phospholipids and protein; found in intestinal lymphatics (lacteals) and blood during and after meals.

chylomicron test
in chilled serum, chylomicrons rise to form a creamy top layer and the serum clears; very low-density lipoproteins remain dispersed and the serum is turbid. Called also the refrigeration test.
References in periodicals archive ?
Table 1: Classification of lipid-based pharmaceutical carriers Lipid-based pharmaceutical carriers Lipoproteins Lipid Lipid Liposomes nanoparticles nanocapsules Chylomicron Solid lipid Conventional nanoparticles liposomes Very low-density Nanostructured Modified lipoprotein lipid carriers lipisomes (VLDL) Intermediate- Lipid drug density conjugates lipoprotein (IDL) Low-density lipoprotein (LDL) High-density lipoprotein (HDL) Table 2: Physicochemical properties of lipoproteins7 [7] Lipoprotein Transport Route Size(nm) Protein Total (%) lipids (%) Chylomicron Intestines to liver 75-1200 1.
This dialysis also permitted analysis of the platelet and chylomicron fractions for brevetoxin binding, and approximately 25% of the binding was to platelets and 2.
The [epsilon]2 allele is associated with increased circulating apoE and, therefore, up-regulation of LDL receptor activity and delayed clearance of chylomicron remnants by the liver (Fullerton et al.
The VLDL and chylomicron particles of these patients are large and appear to lack atherogenic potential.
LDL, VLDL and chylomicrons react with PVS and PEGME and that results in inaccessibility of LDL, VLDL and chylomicron to cholesterol oxidase and cholesterol esterase, whereas HDL reacts with the enzymes.
Effect of Atorvastitin on chylomicron remnant metabolism in visceral obesity: a study employing a new stable isotope breath test.
Inappropriate attention was given to the hypercholesterolaemia, and the disproportionate rise in triglyceride concentration was not recognised as the clue to elevated chylomicron concentration.
Non-high-density lipoprotein (HDL) cholesterol is defined as the difference between total and HDL cholesterol and includes potential proatherogenic apolipoprotein B-containing particles such as low-density lipoprotein (LDL), intermediate-density lipoprotein and very-low-density lipoprotein as well as chylomicron remnants and lipoprotein (a) (1).
Other atherogenic lipoprotein particles, including chylomicron and VLDL remnants, abnormal remnant composition, and increased apolipoprotein C-III complicate the metabolic syndrome picture as well, said Dr.
Objective: This study aimed to investigate effects of chronic black tea consumption on concentrations of chylomicrons and chylomicron remnants using plasma concentrations of apolipoprotein B-48 as a marker.
Fatty acid composition of an oral load affects chylomicron size in human subjects.