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chylomicron

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
chylomicron /chy·lo·mi·cron/ (-mi´kron) a class of lipoproteins that transport exogenous (dietary) cholesterol and triglycerides after meals from the small intestine to tissues for degradation to chylomicron remnants.
chy·lo·mi·cron (kl-mkrn)
n.
One of the microscopic particles of fat occurring in chyle and in the blood, especially after a meal high in fat.

chylomicron
[kī′lōmī′kron]
Etymology: Gk, chylos + mikros, small
minute lipoproteins measuring less than 0.5 μm in diameter. Chylomicrons consist of about 90 triglycerides with small amounts of cholesterol, phospholipids, fat-soluble vitamins, and protein. They are synthesized in the GI tract and carry dietary fat from the intestinal mucosa via the thoracic lymphatic duct into the plasma and ultimately to the liver and tissues. The remnant chylomicron particles are removed by the liver.

chylomicron [ki″lo-mi´kron]
a particle of the class of lipoproteins responsible for the transport of exogenous cholesterol and triglycerides from the small intestine to tissues after meals. Chylomicrons are spherical particles with a core of triglycerides surrounded by a layer of phospholipids, cholesterol, and apolipoproteins.

chylomicron
a stable droplet containing principally triglyceride fat, but also cholesterol, phospholipids and protein; found in intestinal lymphatics (lacteals) and blood during and after meals.

chylomicron test
in chilled serum, chylomicrons rise to form a creamy top layer and the serum clears; very low-density lipoproteins remain dispersed and the serum is turbid. Called also the refrigeration test.


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These particles are released into the lymph in the thoracic duct, finally ending up in the liver where the chylomicron particle is disintegrated and the content is used in the synthesis of non-polar lipids such as triglycerides and cholesteryl esters.
The first reagent contains a-cyclodextrin and dextran sulfate to stabilize LDL-C, VLDL, and chylomicrons.
Medium-chain triglycerides, though not necessarily destined to chylomicrons, could still undergo chain elongation and enter chylomicrons and thus aggravate hypertriglyceridaemia.
 
 
 
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