chronic tubulointerstitial nephritis

chronic tubulointerstitial nephritis

tubulointerstitial nephritis that has progressed to the point at which there is interstitial fibrosis with shrunken kidneys, a lowered glomerular filtration rate, and danger of renal failure.
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The renal parenchymal changes common to all of the above conditions are marked chronic tubulointerstitial nephritis, with disproportionately milder glomerular or vascular changes.
8) Taken together, this suggests that dRTA associated with a positive anti-Ro antibody, typical chronic tubulointerstitial nephritis and the exclusion of other autoimmune disorders may be the forme fruste of primary Sjogren syndrome, even without subjective sicca syndrome.
Urinary obstruction causes irreversible renal failure by inducing chronic tubulointerstitial nephritis.

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