chronic toxicity


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chronic toxicity

Toxicology A condition caused by repeated or long-term exposure to low doses of a toxic substance
References in periodicals archive ?
For the OECD TG 453 carcinogenicity and chronic toxicity protocol the minimal number of animals is 480; for the OECD TG 443, the minimal number is 1,760 and for the NTP MOG Reproduction Study, it is 3,200 animals (Table 1).
The results of the chronic toxicity tests, not including sampling sites where acute effects were detected, are shown in Table 2.
Chronic toxicity studies are carried out to provide information about the possible health hazards likely to arise from repeated exposure over a relatively limited period of time including information about target organs, the possibilities of cumulative effects, and an estimate of the dose at which there is no observed adverse effect.
Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyalella azteca).
As far as we know this is the first study to characterise the acute and chronic toxicity of the herb in mice.
Chronic toxicity is a measure of how poisonous a pesticide is after repeated exposures over a period of time.
Acute and chronic toxicity was intermittently measured in the Coyote Creek tributary.
This is clearly the case for acute toxicity, but the issue becomes murky when we deal with chronic toxicity, which may manifest itself in subtle effects.
Table 1 Toxicity classification * of nickel chemicals Health issues Nickel metal Nickel sulphate Acute oral None Xn:R22 Acute inhalation None Xn:R20 Skin irritant None Xi: R38 Eye irritation None None Skin sensitisation R43 + R43 ^ Respiratory sensitisation None R42 Chronic toxicity T: R48/23 T: R48/23 Reproductive toxicity None Cat.
short-term chronic toxicity of photocatalytic nanoparticles to bacteria and algae, and
Years ago, Professor DG Steyn, professor of pharmacology at the University of Pretoria, pointed out that, "Fluoride is the most dangerous poison from the chronic toxicity point of view, and it might take 40 years or more before its toxic effects may be discernible.

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